2BMA

The crystal structure of Plasmodium falciparum glutamate dehydrogenase, a putative target for novel antimalarial drugs

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	MPG/DESY, HAMBURG BEAMLINE BW6
Synchrotron site	MPG/DESY, HAMBURG
Beamline	BW6
Temperature [K]	100
Detector technology	CCD
Collection date	2001-08-22
Detector	MARRESEARCH
Spacegroup name	C 1 2 1
Unit cell lengths	167.612, 96.851, 196.192
Unit cell angles	90.00, 91.72, 90.00

Refinement procedure

Resolution	100.000 - 2.700
R-factor	0.2489
Rwork	0.249
R-free	0.27680
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	1bgv
RMSD bond length	0.009
RMSD bond angle	1.320
Data reduction software	DENZO
Data scaling software	SCALEPACK
Phasing software	AMoRE
Refinement software	CNS (1.0)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	100.000	2.750
High resolution limit [Å]	2.700	2.700
Rmerge	0.120	0.400
Number of reflections	82010
Completeness [%]	93.3	84.7
Redundancy	1.2

Crystallization Conditions

crystal ID	method	pH	temperature	details
1		8		pH 8.00