2ADA

ATOMIC STRUCTURE OF ADENOSINE DEAMINASE COMPLEXED WITH A TRANSITION-STATE ANALOG: UNDERSTANDING CATALYSIS AND IMMUNODEFICIENCY MUTATIONS

Replaces:  1ADA

Experimental procedure

Spacegroup name	C 1 2 1
Unit cell lengths	102.360, 94.110, 72.930
Unit cell angles	90.00, 127.19, 90.00

Refinement procedure

Resolution	10.000 - 2.400
R-factor	0.195
Rwork	0.195
RMSD bond length	0.003
RMSD bond angle	1.366
Phasing software	X-PLOR
Refinement software	X-PLOR

Data quality characteristics

	Overall
High resolution limit [Å]	2.400 *
Rmerge	0.032 *
Total number of observations	72059 *
Number of reflections	20445
Completeness [%]	93.0

Crystallization Reagents in Literatures

ID	crystal ID	solution	reagent name	concentration (unit)	details
1	1	drop	protein	7 (mg/ml)
2	1	drop		50 (mM)
3	1	drop	sodium citrate	50 (mM)
4	1	drop	PEG6000	7.5 (%)
5	1	reservoir	PEG6000	15 (%)