1YHO
Solution structure of human dihydrofolate reductase complexed with trimethoprim and nadph, 25 structures
Spectrometer
Experimental method: SOLUTION NMR
Spectrometer ID | Spectrometer maker | Spectrometer model | Spectrometer type | Spectrometer field strength |
1 | Varian | UNITYPLUS | 800 | |
2 | Varian | INOVA | 600 |
Experiment
experiment id | conditions id | solution id | Experiment type |
1 | 1 | 1 | 2D NOESY |
10 | 1 | 1 | HNCO |
11 | 1 | 1 | HN(CO)CA |
12 | 1 | 1 | HNCACB |
13 | 1 | 1 | CBCA(CO)NH |
14 | 1 | 1 | HBHA(CO)NH |
15 | 1 | 1 | HCCH-TOCSY |
2 | 1 | 1 | 2D COSY |
3 | 1 | 1 | 15N-HSQC |
4 | 1 | 1 | 13C-HSQC |
5 | 1 | 1 | 13C-NOESY-HSQC |
6 | 1 | 1 | 15N-NOESY-HSQC |
7 | 1 | 1 | 15N-REJECTED-NOESY |
8 | 1 | 1 | 13C-REJECTED-NOESY |
9 | 1 | 1 | HNCA |
NMR Sample
conditions id | NMR sample pH | NMR sample pressure | NMR sample temperature |
1 | 6.5 | 1 | 288 |
Conformers
Conformers Calculated Total Number | 40 |
Conformers Submitted Total Number | 25 |