1YHO
Solution structure of human dihydrofolate reductase complexed with trimethoprim and nadph, 25 structures
Spectrometer
Experimental method: SOLUTION NMR
| Spectrometer ID | Spectrometer maker | Spectrometer model | Spectrometer type | Spectrometer field strength |
| 1 | Varian | UNITYPLUS | 800 | |
| 2 | Varian | INOVA | 600 |
Experiment
| experiment id | conditions id | solution id | Experiment type |
| 1 | 1 | 1 | 2D NOESY |
| 10 | 1 | 1 | HNCO |
| 11 | 1 | 1 | HN(CO)CA |
| 12 | 1 | 1 | HNCACB |
| 13 | 1 | 1 | CBCA(CO)NH |
| 14 | 1 | 1 | HBHA(CO)NH |
| 15 | 1 | 1 | HCCH-TOCSY |
| 2 | 1 | 1 | 2D COSY |
| 3 | 1 | 1 | 15N-HSQC |
| 4 | 1 | 1 | 13C-HSQC |
| 5 | 1 | 1 | 13C-NOESY-HSQC |
| 6 | 1 | 1 | 15N-NOESY-HSQC |
| 7 | 1 | 1 | 15N-REJECTED-NOESY |
| 8 | 1 | 1 | 13C-REJECTED-NOESY |
| 9 | 1 | 1 | HNCA |
NMR Sample
| conditions id | NMR sample pH | NMR sample pressure | NMR sample temperature |
| 1 | 6.5 | 1 | 288 |
Conformers
| Conformers Calculated Total Number | 40 |
| Conformers Submitted Total Number | 25 |
