1XAN

HUMAN GLUTATHIONE REDUCTASE IN COMPLEX WITH A XANTHENE INHIBITOR

Experimental procedure

Spacegroup name	C 1 2 1
Unit cell lengths	119.790, 63.350, 84.650
Unit cell angles	90.00, 58.61, 90.00

Refinement procedure

Resolution	10.000 - 2.000
R-factor	0.158
Rwork	0.158
Phasing software	X-PLOR
Refinement software	X-PLOR

Data quality characteristics

	Overall
High resolution limit [Å]	2.000 *
Rmerge	0.071 *
Number of reflections	33736 *
Completeness [%]	92.0 *

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	Vapor diffusion, hanging drop *	7 *

Crystallization Reagents in Literatures

ID	crystal ID	solution	reagent name	concentration (unit)	details
1	1	drop	hGR	20 (mg/ml)
2	1	drop	ammonium sulfate	3 (%)
3	1	drop	potassium phosphate	0.1 (M)
4	1	drop	beta-octylglucoside	0.1 (%)
5	1	reservoir	ammonium sulfate	21-23 (%)
6	1	reservoir	potassium phosphate	0.1 (M)