1W83
p38 Kinase crystal structure in complex with small molecule inhibitor
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | ROTATING ANODE |
Temperature [K] | 100 |
Spacegroup name | P 21 21 21 |
Unit cell lengths | 45.681, 86.101, 126.079 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Resolution | 19.920 - 2.500 |
R-factor | 0.233 |
Rwork | 0.228 |
R-free | 0.32200 |
Structure solution method | OTHER |
RMSD bond length | 0.015 |
RMSD bond angle | 1.710 |
Refinement software | REFMAC (5.2.0003A) |
Data quality characteristics
Overall | |
Low resolution limit [Å] | 50.000 |
High resolution limit [Å] | 2.500 |
Rmerge | 0.150 |
Number of reflections | 17439 |
<I/σ(I)> | 2.6 |
Completeness [%] | 97.7 |
Redundancy | 2.4 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 |