1TLM

STRUCTURAL ASPECTS OF INOTROPIC BIPYRIDINE BINDING: CRYSTAL STRUCTURE DETERMINATION TO 1.9 ANGSTROMS OF THE HUMAN SERUM TRANSTHYRETIN-MILRINONE COMPLEX

Experimental procedure

Spacegroup name	P 21 21 2
Unit cell lengths	44.178, 86.384, 66.212
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	8.000 - 1.900
R-factor	0.173
RMSD bond length	0.020
RMSD bond angle	0.060
Refinement software	PROLSQ

Data quality characteristics

	Overall	Outer shell
High resolution limit [Å]	1.890 *	1.890 *
Rmerge	0.060 *
Total number of observations	46029 *
Number of reflections	16482 *
Completeness [%]	79.0 *	36 *

Crystallization Reagents in Literatures

ID	crystal ID	solution	reagent name	concentration (unit)	details
1	1	drop	phosphate	0.1 (M)
2	1	drop	1,2,3-heptanetriol	0.25 (%(w/v))
3	1	reservoir	ammonium sulfate