1PSA

STRUCTURE OF A PEPSIN(SLASH)RENIN INHIBITOR COMPLEX REVEALS A NOVEL CRYSTAL PACKING INDUCED BY MINOR CHEMICAL ALTERATIONS IN THE INHIBITOR

Experimental procedure

Spacegroup name	P 1 1 21
格子定数 [Å]	54.100, 74.400, 76.500
格子定数 [度]	90.00, 90.00, 100.80

精密化法

残基	8.000 - 2.900
R因子	0.139 *
Rwork	0.139
結合長の平均二乗偏差(RMSD) [Å]	0.014
結合角の平均二乗偏差(RMSD) [度]	3.170
Refinement software	X-PLOR

Quality characteristics

	Overall
分解能 [Å] (低)	3.000 *
分解能 [Å] (高)	2.900 *
Rmerge_l_obs	0.044 *
Total number of observations	24379 *
独立反射数	11951 *
完全性 [%]	87.0 *

結晶化条件

結晶ID	方法	pH	温度	溶液条件
1	unknown *	2 *		taken from Andreeva, N.S. et al (1984). J. Biol. Chem., 259, 11353-11365. *

文献の結晶化試薬

ID	結晶ID	溶液	試薬名	濃度 (単位) (単位)	詳細
1	1	1	enzyme	20 (mg/ml)
2	1	1	ethanol	20 (%)
3	1	1	sulfuric acid	2.5 (M)