1NPW

Crystal structure of HIV protease complexed with LGZ479

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Source details	RIGAKU RU300
Temperature [K]	298
Detector technology	IMAGE PLATE
Collection date	1999-01-01
Detector	RIGAKU RAXIS II
Spacegroup name	P 21 21 2
Unit cell lengths	58.600, 87.400, 46.700
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	6.000 * - 2.000
R-factor	0.188
Rwork	0.188
Structure solution method	MOLECULAR REPLACEMENT
Data reduction software	DENZO
Data scaling software	SCALEPACK
Phasing software	X-PLOR
Refinement software	X-PLOR

Data quality characteristics

	Overall
Low resolution limit [Å]	30.000
High resolution limit [Å]	2.000
Number of reflections	14186
<I/σ(I)>	7.2
Completeness [%]	84.2
Redundancy	5

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	unknown *	5.2	298	600mM NaCl, 100mM Sodium Acetate buffer, pH 5.2, VAPOR DIFFUSION, HANGING DROP, temperature 298K