1IDB
Crystal structures of HIV-2 protease in complex with inhibitors containing the hydroxyethylamine dipeptide isostere
Experimental procedure
Spacegroup name | P 43 21 2 |
Unit cell lengths | 62.600, 62.600, 115.800 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Resolution | 6.000 - 2.200 |
R-factor | 0.18 |
Rwork | 0.180 |
RMSD bond length | 0.017 |
RMSD bond angle | 2.600 |
Phasing software | X-PLOR |
Refinement software | TNT |
Data quality characteristics
Overall | |
Number of reflections | 10200 * |
Completeness [%] | 87.0 * |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | Vapor diffusion, hanging drop * | 5.4 * |
Crystallization Reagents in Literatures
ID | crystal ID | solution | reagent name | concentration (unit) | details |
1 | 1 | drop | protein | 6 (mg/ml) | |
2 | 1 | drop | phosphate | 10 (%(v/v)) | |
3 | 1 | drop | 0.02 (%(w/v)) | ||
4 | 1 | reservoir | 0.3-0.5 (M) | ||
5 | 1 | reservoir | sodium acetate | 0.1 (M) | |
6 | 1 | reservoir | 0.02 (%(w/v)) |