1FKB

ATOMIC STRUCTURE OF THE RAPAMYCIN HUMAN IMMUNOPHILIN FKBP-12 COMPLEX

Experimental procedure

Spacegroup name	P 21 21 21
Unit cell lengths	45.420, 49.160, 54.740
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	10.000 - 1.700
R-factor	0.165 *
Rwork	0.165
RMSD bond length	0.010
RMSD bond angle	2.800
Phasing software	MERLOT
Refinement software	X-PLOR

Data quality characteristics

	Overall
High resolution limit [Å]	1.700 *
Rmerge	0.056 *
Total number of observations	81484 *
Number of reflections	12991 *
Completeness [%]	93.0 *

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	Vapor diffusion, hanging drop *	6 *

Crystallization Reagents in Literatures

ID	crystal ID	solution	reagent name	concentration (unit)	details
1	1	drop	protein complex	10 (mg/ml)
2	1	reservoir	ammonium sulphate	300 (mM)
3	1	reservoir	phosphate	100 (mM)