1ELC

Analogous inhibitors of elastase do not always bind analogously

Experimental procedure

Spacegroup name	P 21 21 21
Unit cell lengths	51.200, 58.000, 75.460
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	10.000 - 1.750
R-factor	0.15
Rwork	0.150
Phasing software	X-PLOR
Refinement software	X-PLOR

Data quality characteristics

	Overall
Low resolution limit [Å]	10.000 *
High resolution limit [Å]	1.750 *

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	Vapor diffusion *	5 *		THE COMPLEX WAS CO-CRYSTALLIZED. THE CO-CRYSTALS WERE GROWN BY THE METHOD OF VAPOR DIFFUSION IN 40 MICROLITER DROPS CONTAINING 9MG(SLASH)ML OF ELASTASE, 0.1 MILLIMOLAR TFA-LYS-PRO-ISO, 1.4 MILLIMOLAR SODIUM SULFATE AND 100 MILLIMOLAR SODIUM ACETATE AT PH 5. THE RESERVOIR CONSISTED OF 100 MILLIMOLAR SODIUM SULFATE AND 100 MILLIMOLAR ACETATE BUFFER AT PH 5.

Crystallization Reagents in Literatures

ID	crystal ID	solution	reagent name	concentration (unit)	details
1	1	reservoir	methanol	70 (%)
2	1	reservoir	acetate	30 (%)