1TKZ

CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW429576

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SRS BEAMLINE PX7.2
Synchrotron site	SRS
Beamline	PX7.2
Temperature [K]	100
Detector technology	IMAGE PLATE
Collection date	1997-08-10
Detector	MARRESEARCH
Wavelength(s)	1.488
Spacegroup name	P 21 21 21
Unit cell lengths	137.800, 115.200, 65.000
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	29.810 - 2.810
R-factor	0.206
Rwork	0.206
R-free	0.28300
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.010
RMSD bond angle	1.500
Data reduction software	DENZO
Data scaling software	SCALEPACK
Phasing software	X-PLOR
Refinement software	CNS (1.1)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	30.000	2.900
High resolution limit [Å]	2.810	2.810
Rmerge	0.104	0.474
Number of reflections	24383
<I/σ(I)>	9.1	1.35
Completeness [%]	93.8	84.7
Redundancy	2.69	2

Crystallization Conditions

crystal ID	method	pH	temperature	details
1