1TKX

CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW490745

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	PHOTON FACTORY BEAMLINE BL-6A
Synchrotron site	Photon Factory
Beamline	BL-6A
Temperature [K]	289
Detector technology	IMAGE PLATE
Collection date	1998-06-04
Detector	FUJI
Wavelength(s)	1.000
Spacegroup name	P 21 21 21
Unit cell lengths	138.200, 109.700, 72.800
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	29.630 - 2.850
R-factor	0.216
Rwork	0.216
R-free	0.28700
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.008
RMSD bond angle	1.400
Data reduction software	DENZO
Data scaling software	SCALEPACK
Phasing software	X-PLOR
Refinement software	CNS (1.1)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	30.000	2.950
High resolution limit [Å]	2.850	2.850
Rmerge	0.154	0.529
Number of reflections	26084
<I/σ(I)>	5.6	0.9
Completeness [%]	98.2	94.9
Redundancy	4.05	2.76

Crystallization Conditions

crystal ID	method	pH	temperature	details
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