1TKT

CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW426318

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SRS BEAMLINE PX7.2
Synchrotron site	SRS
Beamline	PX7.2
Temperature [K]	100
Detector technology	IMAGE PLATE
Collection date	1997-08-10
Detector	MARRESEARCH
Wavelength(s)	1.488
Spacegroup name	P 21 21 21
Unit cell lengths	138.200, 115.100, 65.200
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	29.830 - 2.600
R-factor	0.208
Rwork	0.208
R-free	0.28200
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.011
RMSD bond angle	1.600
Data reduction software	DENZO
Data scaling software	SCALEPACK
Phasing software	X-PLOR
Refinement software	CNS (1.1)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	30.000	2.690
High resolution limit [Å]	2.600	2.600
Rmerge	0.087	0.451
Number of reflections	28424
<I/σ(I)>	9.53	1.2
Completeness [%]	86.1	74.6
Redundancy	2.57	1.9

Crystallization Conditions

crystal ID	method	pH	temperature	details
1