1SQO

Substituted 2-Naphthamidine Inhibitors of Urokinase

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Spacegroup name	P 21 21 21
Unit cell lengths	55.160, 53.000, 82.300
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	10.000 - 1.840
R-factor	0.222
Rwork	0.222
R-free	0.28400
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.026
RMSD bond angle	2.800
Refinement software	X-PLOR (98.0)

Data quality characteristics

	Overall
Low resolution limit [Å]	19.200
High resolution limit [Å]	1.840
Number of reflections	20009

Crystallization Conditions

crystal ID	method	pH	temperature	details
1