1IVB

STRUCTURES OF AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE

Experimental procedure

Spacegroup name	P 4 21 2
Unit cell lengths	124.540, 124.540, 71.820
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	6.500 - 2.400
R-factor	0.189
Rwork	0.189
RMSD bond length	0.016
RMSD bond angle	2.142
Phasing software	X-PLOR
Refinement software	X-PLOR

Data quality characteristics

	Overall
Rmerge	0.104 *
Number of reflections	15271

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	Vapor diffusion, hanging drop *	7.4 *		Lin, Y., (1990) J. Mol. Biol., 214, 639. *

Crystallization Reagents in Literatures

ID	crystal ID	solution	reagent name	concentration (unit)	details
1	1	drop	PEG4000	10 (%(v/v))
2	1	drop	HEPES	0.01 (M)
3	1	drop		10 (mM)
4	1	drop		2.5 (mM)
5	1	reservoir	PEG4000	20 (%(v/v))
6	1	reservoir	HEPES	0.02 (M)