1ILR

CRYSTAL STRUCTURE OF THE INTERLEUKIN-1 RECEPTOR ANTAGONIST

Experimental procedure

Spacegroup name	P 43 21 2
Unit cell lengths	71.300, 71.300, 117.300
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	8.000 - 2.100
R-factor	0.197
Rwork	0.197
RMSD bond length	0.008
RMSD bond angle	1.500
Phasing software	X-PLOR
Refinement software	X-PLOR

Data quality characteristics

	Overall	Outer shell
High resolution limit [Å]	2.100 *	2.100 *
Number of reflections	16972 *
Completeness [%]	92.7 *	60.1 *

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	Vapor diffusion, hanging drop *		4 *

Crystallization Reagents in Literatures

ID	crystal ID	solution	reagent name	concentration (unit)	details
1	1	drop	PEG8000	5 (%)
2	1	drop	Tris-HCl	100 (mM)
3	1	drop	ammonium acetate	100 (mM)
4	1	drop	IL-1ra	20 (mg/ml)
5	1	drop		30 (mM)
6	1	drop	sodium phosphate	10 (mM)
7	1	reservoir	PEG8000	30 (%)