1D4S

HIV-1 PROTEASE V82F/I84V DOUBLE MUTANT/TIPRANAVIR COMPLEX

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Source details	SIEMENS
Temperature [K]	298
Detector technology	AREA DETECTOR
Collection date	1995-06-11
Detector	SIEMENS
Spacegroup name	P 21 21 2
Unit cell lengths	58.730, 86.680, 46.210
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	10.000 - 2.500
R-free	0.29400
Structure solution method	MOLECULAR REPLACEMENT
Data reduction software	X-GEN
Data scaling software	X-GEN
Phasing software	MERLOT
Refinement software	SHELXL-97

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	10.000	2.660
High resolution limit [Å]	2.500	2.500
Rmerge	0.130	0.396
Number of reflections	8612
<I/σ(I)>	4.9	1.9
Completeness [%]	100.0	99.5
Redundancy	3.4	2.8

Crystallization Conditions

crystal ID	method	pH	temperature	details
1		5.4		none *