8WRD
| Transporter apo state | Descriptor: | FabH, FabL, Synaptic vesicular amine transporter | Authors: | Im, D, Iwata, S. | Deposit date: | 2023-10-13 | Release date: | 2024-09-25 | Last modified: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Neurotransmitter recognition by human vesicular monoamine transporter 2. Nat Commun, 15, 2024
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8WRE
| Transporter bound with dopamine | Descriptor: | FabH, FabL, L-DOPAMINE, ... | Authors: | Im, D, Iwata, S. | Deposit date: | 2023-10-13 | Release date: | 2024-09-25 | Last modified: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Neurotransmitter recognition by human vesicular monoamine transporter 2. Nat Commun, 15, 2024
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8WTW
| Cryo-EM structure of noradrenaline transporter in complex with a x-MrlA analogue | Descriptor: | CHLORIDE ION, MrlA, SODIUM ION, ... | Authors: | Zhao, Y, Hu, T, Yu, Z. | Deposit date: | 2023-10-19 | Release date: | 2024-08-07 | Last modified: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Transport and inhibition mechanisms of the human noradrenaline transporter. Nature, 632, 2024
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8WU1
| Cryo-EM structure of CB1-beta-arrestin1 complex | Descriptor: | Beta-arrestin-1, Cannabinoid receptor 1,Vasopressin V2 receptor, Fab30 heavy chain, ... | Authors: | Liao, Y, Zhang, H, Shen, Q, Cai, C. | Deposit date: | 2023-10-19 | Release date: | 2024-03-20 | Last modified: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Snapshot of the cannabinoid receptor 1-arrestin complex unravels the biased signaling mechanism. Cell, 186, 2023
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8WVG
| Transporter bound with inhibitor | Descriptor: | (3~{S},11~{b}~{R})-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11~{b}-hexahydrobenzo[a]quinolizin-2-one, FabH, FabL, ... | Authors: | Im, D, Iwata, S. | Deposit date: | 2023-10-23 | Release date: | 2024-09-25 | Last modified: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Neurotransmitter recognition by human vesicular monoamine transporter 2. Nat Commun, 15, 2024
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8X2K
| OEA bound GPR3-Gs complex structure | Descriptor: | (Z)-N-(2-hydroxyethyl)octadec-9-enamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Geng, C, Yang, D, Jun, X. | Deposit date: | 2023-11-09 | Release date: | 2024-04-03 | Last modified: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Structural and functional characterization of the endogenous agonist for orphan receptor GPR3. Cell Res., 34, 2024
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8Y1R
| in situ room temperature Laue crystallography | Descriptor: | Lysozyme C | Authors: | Wang, Z.J, Wang, S.S, Pan, Q.Y, Yu, L, Su, Z.H, Yang, T.Y, Wang, Y.Z, Zhang, W.Z, Hao, Q, Gao, X.Y. | Deposit date: | 2024-01-25 | Release date: | 2024-02-07 | Last modified: | 2024-10-02 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Single pulse data collection with an X-ray chopper at in situ room temperature Laue crystallography beamline BL03HB Nucl Instrum Methods Phys Res A, 1069, 2024
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8YEJ
| Cryo-EM structure of the channelrhodopsin GtCCR2 focused on the monomer | Descriptor: | GtCCR2, RETINAL | Authors: | Tanaka, T, Iida, W, Sano, F.K, Oda, K, Shihoya, W, Nureki, O. | Deposit date: | 2024-02-22 | Release date: | 2024-09-04 | Last modified: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4. Mol.Cell, 84, 2024
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8YEK
| Cryo-EM structure of the channelrhodopsin GtCCR2 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GtCCR2, RETINAL | Authors: | Tanaka, T, Iida, W, Sano, F.K, Oda, K, Shihoya, W, Nureki, O. | Deposit date: | 2024-02-22 | Release date: | 2024-09-04 | Last modified: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4. Mol.Cell, 84, 2024
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8YEL
| Cryo-EM structure of the channelrhodopsin GtCCR4 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cation channel rhodopsin 4, RETINAL | Authors: | Tanaka, T, Iida, W, Sano, F.K, Oda, K, Shihoya, W, Nureki, O. | Deposit date: | 2024-02-22 | Release date: | 2024-09-04 | Last modified: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4. Mol.Cell, 84, 2024
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8ZRZ
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9ASH
| Cryo-EM structure of the active Lactococcus lactis Csm bound to target in post-cleavage stage | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR RNA, CRISPR system Cms endoribonuclease Csm3, ... | Authors: | Wang, B, Goswami, H.N, Li, H. | Deposit date: | 2024-02-25 | Release date: | 2024-08-14 | Last modified: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (2.58 Å) | Cite: | Molecular basis for cA6 synthesis by a type III-A CRISPR-Cas enzyme and its conversion to cA4 production. Nucleic Acids Res., 52, 2024
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9ASI
| Cryo-EM structure of the active Lactococcus lactis Csm bound to target in pre-cleavage stage | Descriptor: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CRISPR RNA, ... | Authors: | Wang, B, Goswami, H.N, Li, H. | Deposit date: | 2024-02-25 | Release date: | 2024-08-14 | Last modified: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Molecular basis for cA6 synthesis by a type III-A CRISPR-Cas enzyme and its conversion to cA4 production. Nucleic Acids Res., 52, 2024
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9AT9
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9AU3
| Crystal structure of GenB2 in complex with G418 | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 6'-epimerase, C-6' aminotransferase, ... | Authors: | De Oliveira, G.S, Bury, P.S, Huang, F, Li, Y, Araujo, N.C, Zhou, J, Sun, Y, Leeper, F, Leadlay, P, Dias, M.V.B. | Deposit date: | 2024-02-28 | Release date: | 2024-09-11 | Last modified: | 2024-10-02 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structural and Functional Basis of GenB2 Isomerase Activity from Gentamicin Biosynthesis. Acs Chem.Biol., 19, 2024
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9AUE
| Crystal structure of the holo form of GenB2 in complex with PMP | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 6'-epimerase, C-6' aminotransferase, ... | Authors: | Oliveira, G.S, Bury, P.S, Huang, F, Li, Y, Araujo, N.C, Zhou, J, Sun, Y, Leeper, F, Leadlay, P, Dias, M.V.B. | Deposit date: | 2024-02-29 | Release date: | 2024-09-11 | Last modified: | 2024-10-02 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Structural and Functional Basis of GenB2 Isomerase Activity from Gentamicin Biosynthesis. Acs Chem.Biol., 19, 2024
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9B0C
| Crystal structure of GenB2 in complex with gentamicin X2. | Descriptor: | (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 6'-epimerase, ... | Authors: | Bury, P.S, Araujo, N.C, Oliveira, G.S, Dias, M.V.B. | Deposit date: | 2024-03-11 | Release date: | 2024-09-11 | Last modified: | 2024-10-02 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Structural and Functional Basis of GenB2 Isomerase Activity from Gentamicin Biosynthesis. Acs Chem.Biol., 19, 2024
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9B2H
| HIV-1 wild type protease with GRL-072-17A, a substituted tetrahydrofuran derivative based on Darunavir as P2 group | Descriptor: | 2,5:6,9-dianhydro-1,3,7,8-tetradeoxy-4-O-({(2S,3R)-3-hydroxy-4-[(4-methoxybenzene-1-sulfonyl)(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamoyl)-L-gluco-nonitol, CHLORIDE ION, FORMIC ACID, ... | Authors: | Wang, Y.-F, Agniswamy, J, Ghosh, A.K, Weber, I.T. | Deposit date: | 2024-03-15 | Release date: | 2024-07-24 | Last modified: | 2024-10-02 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Design of substituted tetrahydrofuran derivatives for HIV-1 protease inhibitors: synthesis, biological evaluation, and X-ray structural studies. Org.Biomol.Chem., 22, 2024
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9B8S
| Human polymerase epsilon bound to PCNA and DNA in the nucleotide exchange state | Descriptor: | DNA (5'-D(P*AP*AP*AP*GP*TP*GP*AP*AP*AP*AP*AP*TP*CP*TP*AP*AP*AP*GP*CP*AP*TP*CP*AP*C)-3'), DNA (5'-D(P*GP*TP*GP*AP*TP*GP*CP*TP*TP*TP*AP*GP*AP*TP*TP*TP*TP*TP*C)-3'), DNA polymerase epsilon catalytic subunit A, ... | Authors: | Wang, F, He, Q, Li, H. | Deposit date: | 2024-03-31 | Release date: | 2024-09-11 | Last modified: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (5.01 Å) | Cite: | Structures of the human leading strand Pol epsilon-PCNA holoenzyme. Nat Commun, 15, 2024
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9B8T
| Human polymerase epsilon bound to PCNA and DNA in the nucleotide bound state | Descriptor: | DNA polymerase epsilon catalytic subunit, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | Authors: | Wang, F, He, Q, Li, H. | Deposit date: | 2024-03-31 | Release date: | 2024-09-11 | Last modified: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Structures of the human leading strand Pol epsilon-PCNA holoenzyme. Nat Commun, 15, 2024
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9BF1
| Structure of apo-state V. cholerae DdmD | Descriptor: | Helicase/UvrB N-terminal domain-containing protein | Authors: | Shen, Z.F, Yang, X.Y, Fu, T.M. | Deposit date: | 2024-04-16 | Release date: | 2024-08-21 | Last modified: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | DdmDE eliminates plasmid invasion by DNA-guided DNA targeting. Cell, 187, 2024
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9BF5
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9BJN
| Cryo-EM of Azo-ffspy fiber | Descriptor: | D-peptide ffspy | Authors: | Zia, A, Guo, J, Xu, B, Wang, F. | Deposit date: | 2024-04-25 | Release date: | 2024-09-18 | Last modified: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cell-Free Nonequilibrium Assembly for Hierarchical Protein/Peptide Nanopillars. J.Am.Chem.Soc., 146, 2024
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9BJO
| Cryo-EM of Azo-ffsy fiber | Descriptor: | D-peptide ffsy | Authors: | Zia, A, Guo, J, Xu, B, Wang, F. | Deposit date: | 2024-04-25 | Release date: | 2024-09-18 | Last modified: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cell-Free Nonequilibrium Assembly for Hierarchical Protein/Peptide Nanopillars. J.Am.Chem.Soc., 146, 2024
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9BVD
| Crystal structure of SRY HMG box bound to DNA | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*CP*TP*AP*GP*CP*AP*TP*TP*GP*TP*TP*TP*GP*GP*G)-3'), DNA (5'-D(*GP*CP*CP*CP*AP*AP*AP*CP*AP*AP*TP*GP*CP*TP*AP*GP*TP*G)-3'), ... | Authors: | Georgiadis, M.M. | Deposit date: | 2024-05-20 | Release date: | 2024-09-25 | Last modified: | 2024-10-02 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Role of nucleobase-specific interactions in the binding and bending of DNA by human male sex determination factor SRY. J.Biol.Chem., 300, 2024
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