9MI0
 
 | | 61-12A01 Fab in complex with HIV-1 GT1.1 v4.1 SOSIP Env trimer and RM20A3 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 61_12A01 heavy chain Fv, ... | | Authors: | Phulera, S, Ozorowski, G, Ward, A.B. | | Deposit date: | 2024-12-12 | | Release date: | 2025-05-21 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Precise targeting of HIV broadly neutralizing antibody precursors in humans.
Science, 389, 2025
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9MIA
 | | 206-3G08 Fab in complex with HIV-1 GT1.1 v4.1 SOSIP Env trimer and RM20A3 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 206-3G08 heavy chain Fv, ... | | Authors: | Phulera, S, Ozorowski, G, Ward, A.B. | | Deposit date: | 2024-12-12 | | Release date: | 2025-05-21 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Precise targeting of HIV broadly neutralizing antibody precursors in humans.
Science, 389, 2025
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9MIB
 | | 206-9C09 Fab in complex with HIV-1 GT1.1 v4.1 SOSIP Env trimer and RM20A3 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 206-9C09 heavy chain Fv, ... | | Authors: | Phulera, S, Ozorowski, G, Ward, A.B. | | Deposit date: | 2024-12-12 | | Release date: | 2025-05-21 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Precise targeting of HIV broadly neutralizing antibody precursors in humans.
Science, 389, 2025
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9MIC
 | | Crystal structure of the VRC01-class antibody 4D01, derived from GT1.1 vaccination, in complex with eOD-GT8 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4D01 Fab heavy chain, 4D01 Fab light chain, ... | | Authors: | Agrawal, S, Wilson, I.A. | | Deposit date: | 2024-12-12 | | Release date: | 2025-05-28 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Precise targeting of HIV broadly neutralizing antibody precursors in humans.
Science, 389, 2025
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9MID
 | | Crystal structure of the VRC01-class antibody 3G08, derived from GT1.1 vaccination, in complex with eOD-GT8 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3G08 Fab Heavy Chain, 3G08 Fab Light Chain, ... | | Authors: | Agrawal, S, Wilson, I.A. | | Deposit date: | 2024-12-12 | | Release date: | 2025-05-28 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Precise targeting of HIV broadly neutralizing antibody precursors in humans.
Science, 389, 2025
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9MIF
 | | Crystal structure of the VRC01-class antibody 9C09, derived from GT1.1 vaccination, in complex with eOD-GT8 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 9C09 Fab heavy chain, 9C09 Fab light chain, ... | | Authors: | Agrawal, S, Wilson, I.A. | | Deposit date: | 2024-12-12 | | Release date: | 2025-05-28 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Precise targeting of HIV broadly neutralizing antibody precursors in humans.
Science, 389, 2025
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9MIH
 | | 273-4D01 Fab in complex with HIV-1 BG505 SOSIP Env trimer and RM20A3 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 273-4D01 heavy chain Fv, ... | | Authors: | Phulera, S, Ozorowski, G, Ward, A.B. | | Deposit date: | 2024-12-12 | | Release date: | 2025-05-21 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Precise targeting of HIV broadly neutralizing antibody precursors in humans.
Science, 389, 2025
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9MII
 | | 253-7A03 Fab in complex with HIV-1 BG505 SOSIP Env trimer and RM20A3 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 253-7A03 heavy chain Fv, ... | | Authors: | Phulera, S, Ozorowski, G, Ward, A.B. | | Deposit date: | 2024-12-12 | | Release date: | 2025-05-21 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Precise targeting of HIV broadly neutralizing antibody precursors in humans.
Science, 389, 2025
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9MIP
 | | CryoEM structure of the Protein Phasphatase 2A (Aalpha-B56gamma-Calpha) holoenzyme complex | | Descriptor: | MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... | | Authors: | Day, A, Taylor, D. | | Deposit date: | 2024-12-13 | | Release date: | 2025-07-09 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Regulatory mechanisms of PP2A complex assembly driven by physicochemical differences in A-subunit isoforms.
Structure, 2025
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9MJ3
 | | Crystal structure of the VRC01-class antibody 12A01, derived from GT1.1 vaccination, in complex with eOD-GT8 | | Descriptor: | 12A01 Fab heavy chain, 12A01 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Agrawal, S, Wilson, I.A. | | Deposit date: | 2024-12-13 | | Release date: | 2025-05-28 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Precise targeting of HIV broadly neutralizing antibody precursors in humans.
Science, 389, 2025
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9MJ6
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9MJC
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9MJD
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9MJI
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9MK4
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9MKO
 | | 4D4 TCR bound to R-phycoerythrin | | Descriptor: | 4D4 TCR alpha chain, 4D4 TCR beta chain, PHYCOERYTHROBILIN, ... | | Authors: | Rashleigh, L, Gully, B.S, Rossjohn, J. | | Deposit date: | 2024-12-17 | | Release date: | 2025-08-06 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.21 Å) | | Cite: | Antibody-like recognition of a gamma delta T cell receptor toward a foreign antigen.
Structure, 2025
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9MLG
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9MNN
 | | Crystal structure of L. monocytogenes MenD with Mg2+ and intermediate I bound | | Descriptor: | (4S)-4-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3lambda~5~-thiazol-2-yl}-4-hydroxybutanoic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, MAGNESIUM ION | | Authors: | Klein, M, Given, F.M, Ho, N.A.T, Allison, T.M, Johnston, J.M. | | Deposit date: | 2024-12-22 | | Release date: | 2025-07-30 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Structures of Listeria monocytogenes MenD in ThDP-bound and in-crystallo captured intermediate I-bound forms.
Acta Crystallogr.,Sect.F, 81, 2025
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9MSD
 | | G002-293-0536 Fab in complex with 001428_T278M_L14 SOSIP and RM20A3 Fab | | Descriptor: | 001428_T278M_L14 SOSIP gp140, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Phulera, S, Ozorowski, G, Ward, A.B. | | Deposit date: | 2025-01-09 | | Release date: | 2025-05-28 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Vaccination with mRNA-encoded nanoparticles drives early maturation of HIV bnAb precursors in humans.
Science, 389, 2025
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9MSY
 | | G002-480-0546 Fab in complex with V703-0537_T278M_L14 SOSIP and BG18 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG18 Fab heavy chain, ... | | Authors: | Phulera, S, Ozorowski, G, Ward, A.B. | | Deposit date: | 2025-01-10 | | Release date: | 2025-05-28 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Vaccination with mRNA-encoded nanoparticles drives early maturation of HIV bnAb precursors in humans.
Science, 389, 2025
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9MVO
 | | Crystal Structure of SARS-CoV-2 Main Protease (Mpro) in Complex with Inhibitor AVI-4692 | | Descriptor: | (3M,5P,6M)-5-(1H-1,2,3-benzotriazol-1-yl)-6-(3-chlorophenyl)-3-(isoquinolin-4-yl)-1-(prop-2-en-1-yl)pyrimidine-2,4(1H,3H)-dione, (3M,5P,6M)-5-(1H-1,2,3-benzotriazol-1-yl)-6-(3-chlorophenyl)-3-(isoquinolin-4-yl)-1-(prop-2-yn-1-yl)pyrimidine-2,4(1H,3H)-dione, 3C-like proteinase nsp5 | | Authors: | Diallo, A, Gumpena, R, Verba, K. | | Deposit date: | 2025-01-15 | | Release date: | 2025-07-23 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus M Pro inhibitors with potent in vivo efficacy.
Sci Adv, 11, 2025
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9MVT
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9MVV
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9N1S
 | | Crystal structure of the Transport and Golgi Organization protein 2 Homolog (TANGO2) tetragonal form | | Descriptor: | CHLORIDE ION, PHOSPHATE ION, Transport and Golgi organization protein 2 homolog | | Authors: | Lovell, S, Cooper, A, Powers, A, Battaile, K.P, Moshen, A.W, Ghaloul-Gonzalez, L. | | Deposit date: | 2025-01-27 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The Crystal Structure of Human Transport and Golgi Organization 2 Homolog (TANGO2) Protein Reveals an alpha beta beta alpha-Fold Arrangement.
Proteins, 2025
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9N2D
 | | Cryo-EM structure of an extended F. johnsoniae BAM complex, composite map | | Descriptor: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, Bam A, Bam D, ... | | Authors: | Deme, J.C, Lea, S.M. | | Deposit date: | 2025-01-28 | | Release date: | 2025-07-09 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | An extended BAM complex in the Bacteroidota
To Be Published
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