COVID-19特辑

冠状病毒，2020. 由David S. Goodsell @ RCSB PDB原图修改

最近爆发的新型冠状病毒传染病（Novel Coronavirus disease 2019: COVID-19）对全世界的人们都构成了严重威胁。为了尽早了解新病毒（Severe Acute Respiratory Syndrome Coronavirus 2: SARS-CoV-2）以开发出有效的抗病毒药物，已经有很多科研人員开始了相关蛋白结构的研究，并且将所获得的结构数据存储于PDB。 PDBj为用户提供了COVID-19相关数据一览的门户页面，并将于每周三更新当日新发布的相关数据。

有关该病毒蛋白质的解说，请参见下面的“当月的分子”页面。

“所有结构”标签的页面则逐一罗列了所有的结构数据，包括由同一研究组提交的系列数据群。 “代表性结构”标签的页面精选具有相同氨基酸序列的结构数据中的高分辨率数据，不重复选择具同一氨基酸序列的数据，即使该数据可能包含不同配体。 “最新条目”标签内包含本周新更新数据。

Created: 2020-09-03 (last edited: more than 1 year ago)

所有结构 (4476)代表性结构 (1994)最新条目 (17)

7SDR

Papain-Like Protease of SARS CoV-2 in Complex with Jun9-72-2 Inhibitor
Descriptor:	1,2-ETHANEDIOL, 4-({methyl[(1R)-1-(naphthalen-1-yl)ethyl]amino}methyl)phenol, CHLORIDE ION, ...
Authors:	Osipiuk, J, Tesar, C, Endres, M, Wang, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2021-09-29
Release date:	2021-10-06
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.72 Å)
Cite:	Papain-Like Protease of SARS CoV-2 in Complex with Jun9-72-2 Inhibitor To be Published

7V76

Cryo-EM structure of SARS-CoV-2 S-Beta variant (B.1.351), uncleavable form, one RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Beta variant (B.1.351), uncleavable form, one RBD-up conformation To Be Published

7V77

Cryo-EM structure of SARS-CoV-2 S-Beta variant (B.1.351), uncleavable form, two RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Beta variant (B.1.351), uncleavable form, two RBD-up conformation To Be Published

7V78

Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1), one RBD-up conformation 1
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3.4 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1), one RBD-up conformation 1 To Be Published

7V79

Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1), one RBD-up conformation 2
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1), one RBD-up conformation 2 To Be Published

7V7A

Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1), two RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3.4 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1), two RBD-up conformation To Be Published

7V7D

Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), all RBD-down conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), all RBD-down conformation To Be Published

7V7E

Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), one RBD-up conformation 1
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (2.9 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), one RBD-up conformation 1 To Be Published

7V7F

Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), one RBD-up conformation 2
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (2.9 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), one RBD-up conformation 2 To Be Published

7V7G

Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), two RBD-up conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), two RBD-up conformation To Be Published

7V7H

Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), dimer of S trimer conformation 1
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), dimer of S trimer conformation 1 To Be Published

7V7I

Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), dimer of S trimer conformation 2
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), dimer of S trimer conformation 2 To Be Published

7V7J

Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), dimer of S trimer conformation 3
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3.4 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), dimer of S trimer conformation 3 To Be Published

7V7N

Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), all RBD-down conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (2.9 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), all RBD-down conformation To Be Published

7V7O

Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), one RBD-up conformation 1
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (2.9 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), one RBD-up conformation 1 To Be Published

7V7P

Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), one RBD-up conformation 2
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (2.9 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), one RBD-up conformation 2 To Be Published

7V7Q

Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), one RBD-up conformation 3
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (2.8 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), one RBD-up conformation 3 To Be Published

7V7R

Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), one RBD-up conformation 4
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (2.9 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), one RBD-up conformation 4 To Be Published

7V7S

Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), one RBD-up conformation 5
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), one RBD-up conformation 5 To Be Published

7V7T

Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), two RBD-up conformation 1
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), two RBD-up conformation 1 To Be Published

7V7U

Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), two RBD-up conformation 2
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), two RBD-up conformation 2 To Be Published

7V7V

Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), two RBD-up conformation 3
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-21
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), two RBD-up conformation 3 To Be Published

7V7Z

Cryo-EM structure of SARS-CoV-2 S-Beta variant (B.1.351) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2,Green fluorescent protein, ...
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-22
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Beta variant (B.1.351) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form To Be Published

7V80

Local refinement of SARS-CoV-2 S-Beta variant (B.1.351) RBD and Angiotensin-converting enzyme 2 (ACE2) ectodomain
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2,Green fluorescent protein, ...
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-22
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3.9 Å)
Cite:	Local refinement of SARS-CoV-2 S-Beta variant (B.1.351) RBD and Angiotensin-converting enzyme 2 (ACE2) ectodomain To Be Published

7V81

Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, two ACE2-bound form
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2,Green fluorescent protein, ...
Authors:	Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D.
Deposit date:	2021-08-22
Release date:	2021-10-06
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, two ACE2-bound form To Be Published

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