Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

COVID-19特辑

本页面还有其他语言版本: English日本語繁體中文한국어
冠状病毒
冠状病毒，2020. 由David S. Goodsell @ RCSB PDB原图修改

最近爆发的新型冠状病毒传染病（Novel Coronavirus disease 2019: COVID-19）对全世界的人们都构成了严重威胁。 为了尽早了解新病毒（Severe Acute Respiratory Syndrome Coronavirus 2: SARS-CoV-2）以开发出有效的抗病毒药物，已经有很多科研人員开始了相关蛋白结构的研究，并且将所获得的结构数据存储于PDB。 PDBj为用户提供了COVID-19相关数据一览的门户页面，并将于每周三更新当日新发布的相关数据。

有关该病毒蛋白质的解说，请参见下面的“当月的分子”页面。

“所有结构”标签的页面则逐一罗列了所有的结构数据，包括由同一研究组提交的系列数据群。 “代表性结构”标签的页面精选具有相同氨基酸序列的结构数据中的高分辨率数据，不重复选择具同一氨基酸序列的数据，即使该数据可能包含不同配体。 “最新条目”标签内包含本周新更新数据。

Created: 2020-09-03 (last edited: more than 1 year ago)2020-12-02
所有结构 (5519)代表性结构 (2329)最新条目 (113)
9SAR
DownloadVisualize
BU of 9sar by Molmil
Cryo-EM structure of SARS CoV-2 RdRp wild-type in complex with 20-40mer RNA incorporating ATP
Descriptor: Non-structural protein 7, Non-structural protein 8, RNA primer strand (27-MER), ...
Authors:Oliva, M.F, Das, K.
Deposit date:2025-08-07
Release date:2025-10-01
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis for selective remdesivir incorporation by SARS-CoV-2 RNA polymerase, and S759A resistance.
Biorxiv, 2025
8XZ0
DownloadVisualize
BU of 8xz0 by Molmil
Crystal complex structure of SARS-CoV-2 S bound to human ezrin
Descriptor: Ezrin, Spike protein S2'
Authors:Wang, J.M, Ma, W.F.
Deposit date:2024-01-20
Release date:2025-10-08
Method:X-RAY DIFFRACTION (2.035 Å)
Cite:Crystal complex structure of SARS-CoV-2 S bound to human ezrin
To Be Published
8XZ4
DownloadVisualize
BU of 8xz4 by Molmil
SARS-CoV-2 S and radixin complex structure
Descriptor: Radixin, Spike protein S2'
Authors:Wang, J.M, Ma, W.F.
Deposit date:2024-01-20
Release date:2025-10-08
Method:X-RAY DIFFRACTION (2.129 Å)
Cite:SARS-CoV-2 S and radixin complex structure
To Be Published
8XZ5
DownloadVisualize
BU of 8xz5 by Molmil
SARS-CoV-2 S and moesin complex structure
Descriptor: Moesin, Spike protein S2'
Authors:Wang, J.M, Ma, W.F.
Deposit date:2024-01-20
Release date:2025-10-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:SARS-CoV-2 S and moesin complex structure
To Be Published
9C7S
DownloadVisualize
BU of 9c7s by Molmil
Cryo EM structure of SARS-COV-2 (BQ 1.1) RBD in complex with Fab COV2-3891 (local refine)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab COV-3891 heavy chain, Fab COV-3891 light chain, ...
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2024-06-11
Release date:2025-10-08
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo EM structure of SARS-COV-2 (BQ 1.1) RBD in complex with Fab COV2-3891 (local refine)
To Be Published
9KUR
DownloadVisualize
BU of 9kur by Molmil
Crystal structure of mAb nCoV400Fab with SARS-CoV-2 N-CTD Complex
Descriptor: 400Fab Heavy chain, 400Fab Light chain, Nucleoprotein
Authors:Xue, S.J, Chen, S.D.
Deposit date:2024-12-04
Release date:2025-10-15
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural basis of a human antibody targeting SARS-CoV-2 nucleocapsid protein dimerization domain and interfering with RNA-binding.
Commun Biol, 8, 2025
7IB8
DownloadVisualize
BU of 7ib8 by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X10590 (well A03) from the KIT library
Descriptor: 5-(4-bromophenyl)-1H-tetrazole, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IB9
DownloadVisualize
BU of 7ib9 by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X11415 (well A09) from the KIT library
Descriptor: 3-methylnaphthalen-2-ol, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBA
DownloadVisualize
BU of 7iba by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X13162 (well B06) from the KIT library
Descriptor: 4-(2-aminoethyl)-2-iodophenol, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBB
DownloadVisualize
BU of 7ibb by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X13458 (well B08) from the KIT library
Descriptor: (2-bromo-1,4-phenylene)dimethanol, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBC
DownloadVisualize
BU of 7ibc by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X15604 (well C08) from the KIT library
Descriptor: 2-[(1-methylcyclobutyl)sulfanyl]benzoic acid, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBD
DownloadVisualize
BU of 7ibd by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X2317 (well E01) from the KIT library
Descriptor: (R)-MANDELIC ACID, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBE
DownloadVisualize
BU of 7ibe by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X4071 (well F06) from the KIT library
Descriptor: 2,2,2-trifluoro-1-(1-methyl-1H-imidazol-2-yl)ethan-1-one, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBF
DownloadVisualize
BU of 7ibf by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X4161 (well F07) from the KIT library
Descriptor: (3S)-3-(4-hydroxyphenyl)piperazin-2-one, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBG
DownloadVisualize
BU of 7ibg by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X5449 (well G01) from the KIT library
Descriptor: Host translation inhibitor nsp1, methyl (1S)-2-oxocyclopentane-1-carboxylate
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBH
DownloadVisualize
BU of 7ibh by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X6553 (well G10) from the KIT library
Descriptor: (4-bromanyl-5-methyl-thiophen-2-yl)-oxidanyl-oxidanylidene-boron, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBI
DownloadVisualize
BU of 7ibi by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X7214 (well H02) from the KIT library
Descriptor: Host translation inhibitor nsp1, N,N'-(pyridine-2,6-diyl)diacetamide
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBJ
DownloadVisualize
BU of 7ibj by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A01 (dataset 1) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBK
DownloadVisualize
BU of 7ibk by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A02 (dataset 1) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBL
DownloadVisualize
BU of 7ibl by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A04 (dataset 2) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBM
DownloadVisualize
BU of 7ibm by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A05 (dataset 1) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBN
DownloadVisualize
BU of 7ibn by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A06 (dataset 1) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBO
DownloadVisualize
BU of 7ibo by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A07 (dataset 1) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBP
DownloadVisualize
BU of 7ibp by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A08 (dataset 1) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBQ
DownloadVisualize
BU of 7ibq by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A10 (dataset 1) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025

243531

数据于2025-10-22公开中

PDB statisticsPDBj update infoContact PDBjnumon