신종 코로나바이러스 특집 콘텐츠

이 페이지는 다른 언어로도 제공됩니다: English 日本語简体中文繁體中文

코로나 바이러스, 2020. David S. Goodsell @ RCSB PDB에 의한 오리지널 일러스트를 수정

신종 코로나바이러스 감염증 (Novel Coronavirus disease 2019:COVID-19)의 확산이 세계적으로 매우 큰 문제가 되고 있습니다. 시급히 새로운 바이러스（Severe Acute Respiratory Syndrome Coronavirus 2: SARS-CoV-2）를 이해하고 효과적인 약을 개발하기 위해, 신속하게 구조 생물학 연구가 시작되고 있습니다. PDBj는 사용자의 편의를 도모하기 위해 신종 코로나바이러스의 특집 페이지를 제공하고 있습니다. 매주 수요일에 최신 항목이 추가됩니다.

바이러스 단백질에 관한 해설기사는 아래의 「이달의 분자」 페이지를 참조하십시오.

「전체 엔트리」 탭에는, 모든 PDB ID가 포함되어 있습니다. 이용자가 전체의 독립된 엔트리를 검색하고 싶을 때 사용하실 수 있으며, 동일 저자에 의한 그룹등록의 엔트리도 전부 구별되어 있습니다. 「대표구조」 탭에는, 분해능이 가장 높은 대표구조만을 표지하고 있습니다. 아미노산 서열이 100 % 일치하는 PDB 엔트리의 경우, 다른 리간드를 포함하여도 대표구조에는 제외됩니다. 「최신 엔트리」 탭은, 이번주 공개된 가장 최근의 엔트리 입니다.

Created: 2020-09-03 (last edited: more than 1 year ago)

전체 엔트리 (4406)대표구조 (1944)최신 엔트리 (19)

8YB7

SARS-CoV-2 DMV nsp3-4 pore complex (consensus-pore, C3 symmetry)
Descriptor:	Non-structural protein 4, Papain-like protease nsp3
Authors:	Huang, Y.X, Zhong, L.J, Zhang, W.X, Ni, T.
Deposit date:	2024-02-12
Release date:	2024-06-19
Method:	ELECTRON MICROSCOPY (4.6 Å)
Cite:	Molecular Architecture of Coronavirus Double Membrane Vesicle Pore Complex To Be Published

9EOW

The 5-terminal stem-loop RNA element of SARS-CoV-2 features highly dynamic structural elements that are sensitive to differences in cellular pH
Descriptor:	RNA (29-MER)
Authors:	Wacker, A, Schwalbe, H.
Deposit date:	2024-03-15
Release date:	2024-06-19
Method:	SOLUTION NMR
Cite:	The 5'-terminal stem-loop RNA element of SARS-CoV-2 features highly dynamic structural elements that are sensitive to differences in cellular pH. Nucleic Acids Res., 2024

8T7Y

Structure of SARS CoV-2 main protease in complex with Chymostatin.
Descriptor:	3C-like proteinase nsp5, Chymostatin A (bound form)
Authors:	Terzyan, S, Yarla, N, Rao, C.V, Mooers, B.
Deposit date:	2023-06-21
Release date:	2024-06-26
Method:	X-RAY DIFFRACTION (1.78 Å)
Cite:	Structure of SARS CoV-2 main protease in complex with Chymostatin. to be published

8WHZ

BA.2.86 RBD in complex with hACE2 (local refinement)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Processed angiotensin-converting enzyme 2, ...
Authors:	Yue, C, Liu, P.
Deposit date:	2023-09-23
Release date:	2024-06-26
Method:	ELECTRON MICROSCOPY (3.93 Å)
Cite:	Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity Natl Sci Rev, 2024

8X4Z

BA.2.86 Spike Trimer with ins483V mutation (3 RBD down)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:	Yue, C, Liu, P.
Deposit date:	2023-11-16
Release date:	2024-06-26
Method:	ELECTRON MICROSCOPY (3.49 Å)
Cite:	Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity Natl Sci Rev, 2024

8X50

BA.2.86 Spike Trimer with ins483V mutation (1 RBD up)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:	Yue, C, Liu, P.
Deposit date:	2023-11-16
Release date:	2024-06-26
Method:	ELECTRON MICROSCOPY (3.82 Å)
Cite:	Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity Natl Sci Rev, 2024

8X55

BA.2.86 Spike Trimer with T356K mutation (3 RBD down)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:	Yue, C, Liu, P.
Deposit date:	2023-11-16
Release date:	2024-06-26
Method:	ELECTRON MICROSCOPY (3.75 Å)
Cite:	Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity Natl Sci Rev, 2024

8X56

BA.2.86 Spike Trimer with T356K mutation (1 RBD up)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:	Yue, C, Liu, P.
Deposit date:	2023-11-16
Release date:	2024-06-26
Method:	ELECTRON MICROSCOPY (3.93 Å)
Cite:	Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity Natl Sci Rev, 2024

8JUX

Crystal structure of SARS-CoV-2 Papain-like protease complexed with noncovalent inhibitor SR-01
Descriptor:	MAGNESIUM ION, Non-structural protein 7, ~{N}-[(3-fluorophenyl)methyl]-1-[(1~{R})-1-(3-methoxynaphthalen-1-yl)ethyl]piperidine-4-carboxamide
Authors:	Hsieh, Y.-J, Wu, K.-P.
Deposit date:	2023-06-27
Release date:	2024-07-03
Method:	X-RAY DIFFRACTION (3.2 Å)
Cite:	Crystal structure of SARS-CoV-2 Papain-like protease complexed with noncovalent inhibitor SR-01 To Be Published

8OYT

Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '3 up' RBD conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H6 nanobody, ...
Authors:	Weckener, M, Naismith, J.H, Owens, R.J.
Deposit date:	2023-05-05
Release date:	2024-07-03
Method:	ELECTRON MICROSCOPY (3.8 Å)
Cite:	Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2. Open Biology, 14, 2024

8WHS

Spike Trimer of BA.2.86 in complex with one hACE2
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Processed angiotensin-converting enzyme 2, ...
Authors:	Yue, C, Liu, P.
Deposit date:	2023-09-23
Release date:	2024-07-03
Method:	ELECTRON MICROSCOPY (3.33 Å)
Cite:	Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity Natl Sci Rev, 2024

8WHU

Spike Trimer of BA.2.86 in complex with two hACE2s
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Processed angiotensin-converting enzyme 2, ...
Authors:	Yue, C, Liu, P.
Deposit date:	2023-09-23
Release date:	2024-07-03
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity Natl Sci Rev, 2024

8WHV

Spike Trimer of BA.2.86 with three RBDs down
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:	Yue, C, Liu, P.
Deposit date:	2023-09-23
Release date:	2024-07-03
Method:	ELECTRON MICROSCOPY (3.32 Å)
Cite:	Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity Natl Sci Rev, 2024

8WHW

Spike Trimer of BA.2.86 with single RBD up
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:	Yue, C, Liu, P.
Deposit date:	2023-09-23
Release date:	2024-07-03
Method:	ELECTRON MICROSCOPY (3.85 Å)
Cite:	Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity Natl Sci Rev, 2024

8WP8

Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
Authors:	Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F.
Deposit date:	2023-10-09
Release date:	2024-07-03
Method:	ELECTRON MICROSCOPY (2.89 Å)
Cite:	Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2 To Be Published

8X4H

SARS-CoV-2 JN.1 Spike
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:	Yue, C, Liu, P.
Deposit date:	2023-11-15
Release date:	2024-07-03
Method:	ELECTRON MICROSCOPY (3.65 Å)
Cite:	Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity Natl Sci Rev, 2024

8X5Q

SARS-CoV-2 BA.2.75 Spike with K356T mutation (3 RBD down)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Yue, C, Liu, P.
Deposit date:	2023-11-17
Release date:	2024-07-03
Method:	ELECTRON MICROSCOPY (3.47 Å)
Cite:	Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity Natl Sci Rev, 2024

8X5R

SARS-CoV-2 BA.2.75 Spike with K356T mutation (1 RBD up)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Yue, C, Liu, P.
Deposit date:	2023-11-17
Release date:	2024-07-03
Method:	ELECTRON MICROSCOPY (3.72 Å)
Cite:	Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity Natl Sci Rev, 2024

8XLV

Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P), 1-RBD-up state
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:	2023-12-26
Release date:	2024-07-03
Method:	ELECTRON MICROSCOPY (3.07 Å)
Cite:	Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86, EG.5, EG.5.1 and HV.1 sub-variants To Be Published

8XM5

Cryo-EM structure of SARS-CoV-2 Omicron EG.5 spike protein(6P), RBD-closed state
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:	2023-12-27
Release date:	2024-07-03
Method:	ELECTRON MICROSCOPY (2.61 Å)
Cite:	Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86, EG.5, EG.5.1 and HV.1 sub-variants To Be Published

8XMG

Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P), RBD-closed state
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:	2023-12-27
Release date:	2024-07-03
Method:	ELECTRON MICROSCOPY (2.9 Å)
Cite:	Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86, EG.5, EG.5.1 and HV.1 sub-variants To Be Published

8XMT

Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P), RBD-closed state
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:	2023-12-28
Release date:	2024-07-03
Method:	ELECTRON MICROSCOPY (3.31 Å)
Cite:	Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86, EG.5, EG.5.1 and HV.1 sub-variants To Be Published

8XN2

SARS-CoV-2 Omicron EG.5.1 RBD in complex with human ACE2 (local refined from the spike protein)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ...
Authors:	Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:	2023-12-28
Release date:	2024-07-03
Method:	ELECTRON MICROSCOPY (2.79 Å)
Cite:	Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86, EG.5, EG.5.1 and HV.1 sub-variants To Be Published

8XN3

SARS-CoV-2 Omicron HV.1 RBD in complex with human ACE2 (local refinement from the spike protein)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ...
Authors:	Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:	2023-12-28
Release date:	2024-07-03
Method:	ELECTRON MICROSCOPY (2.64 Å)
Cite:	Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86, EG.5, EG.5.1 and HV.1 sub-variants To Be Published

8XN5

Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P) in complex with human ACE2
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ...
Authors:	Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:	2023-12-29
Release date:	2024-07-03
Method:	ELECTRON MICROSCOPY (2.87 Å)
Cite:	Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86, EG.5, EG.5.1 and HV.1 sub-variants To Be Published

<162 163 164 165 166 167 168 169 170 171 172 173 174175176 177 >

Total results:	4406
Displayed results:	25
Sorted by:	Release date (from oldest)