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Yorodumi- PDB-1rto: PROTON NMR ASSIGNMENTS AND SOLUTION CONFORMATION OF RANTES, A CHE... -
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-Basic information
Entry | Database: PDB / ID: 1rto | ||||||
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Title | PROTON NMR ASSIGNMENTS AND SOLUTION CONFORMATION OF RANTES, A CHEMOKINE OF THE CC TYPE | ||||||
Components | RANTES | ||||||
Keywords | CHEMOKINE / CHEMOTACTIC CYTOKINE | ||||||
Function / homology | Function and homology information regulation of chronic inflammatory response / CCR4 chemokine receptor binding / chemokine receptor antagonist activity / activation of phospholipase D activity / positive regulation of cellular biosynthetic process / CCR1 chemokine receptor binding / positive regulation of natural killer cell chemotaxis / negative regulation of macrophage apoptotic process / chemokine receptor binding / positive regulation of cell-cell adhesion mediated by integrin ...regulation of chronic inflammatory response / CCR4 chemokine receptor binding / chemokine receptor antagonist activity / activation of phospholipase D activity / positive regulation of cellular biosynthetic process / CCR1 chemokine receptor binding / positive regulation of natural killer cell chemotaxis / negative regulation of macrophage apoptotic process / chemokine receptor binding / positive regulation of cell-cell adhesion mediated by integrin / : / receptor signaling protein tyrosine kinase activator activity / CCR5 chemokine receptor binding / positive regulation of T cell chemotaxis / positive regulation of homotypic cell-cell adhesion / negative regulation by host of viral transcription / CCR chemokine receptor binding / neutrophil activation / positive regulation of G protein-coupled receptor signaling pathway / phosphatidylinositol phospholipase C activity / negative regulation of T cell apoptotic process / positive regulation of T cell apoptotic process / positive regulation of calcium ion transport / eosinophil chemotaxis / positive regulation of innate immune response / cellular response to fibroblast growth factor stimulus / positive regulation of monocyte chemotaxis / chemokine-mediated signaling pathway / Chemokine receptors bind chemokines / chemokine activity / regulation of T cell activation / dendritic cell chemotaxis / negative regulation of G protein-coupled receptor signaling pathway / leukocyte cell-cell adhesion / negative regulation of viral genome replication / phospholipase activator activity / positive regulation of macrophage chemotaxis / macrophage chemotaxis / positive regulation of smooth muscle cell migration / chemoattractant activity / exocytosis / monocyte chemotaxis / Interleukin-10 signaling / regulation of insulin secretion / positive regulation of phosphorylation / positive regulation of cell adhesion / cellular response to interleukin-1 / positive regulation of T cell migration / positive regulation of translational initiation / positive regulation of viral genome replication / positive regulation of T cell proliferation / positive regulation of epithelial cell proliferation / positive regulation of tyrosine phosphorylation of STAT protein / epithelial cell proliferation / positive regulation of smooth muscle cell proliferation / cell chemotaxis / positive regulation of receptor signaling pathway via JAK-STAT / response to virus / response to toxic substance / cellular response to virus / cellular response to type II interferon / intracellular calcium ion homeostasis / chemotaxis / calcium ion transport / antimicrobial humoral immune response mediated by antimicrobial peptide / cell-cell signaling / cellular response to tumor necrosis factor / G alpha (i) signalling events / positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / positive regulation of cell migration / protein kinase activity / inflammatory response / G protein-coupled receptor signaling pathway / protein homodimerization activity / extracellular space / extracellular region / identical protein binding / cytoplasm Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | SOLUTION NMR | ||||||
Authors | Skelton, N.J. | ||||||
Citation | Journal: Biochemistry / Year: 1995 Title: Proton NMR assignments and solution conformation of RANTES, a chemokine of the C-C type. Authors: Skelton, N.J. / Aspiras, F. / Ogez, J. / Schall, T.J. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1rto.cif.gz | 48.5 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1rto.ent.gz | 39.6 KB | Display | PDB format |
PDBx/mmJSON format | 1rto.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1rto_validation.pdf.gz | 243.7 KB | Display | wwPDB validaton report |
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Full document | 1rto_full_validation.pdf.gz | 243.5 KB | Display | |
Data in XML | 1rto_validation.xml.gz | 4.7 KB | Display | |
Data in CIF | 1rto_validation.cif.gz | 6.1 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/rt/1rto ftp://data.pdbj.org/pub/pdb/validation_reports/rt/1rto | HTTPS FTP |
-Related structure data
-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein | Mass: 7862.011 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / Production host: Escherichia coli (E. coli) / References: UniProt: P13501 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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-Sample preparation
Crystal grow | *PLUS Method: other / Details: NMR |
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-Processing
Software |
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NMR software |
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NMR ensemble | Conformers submitted total number: 1 |