+Open data
-Basic information
Entry | Database: PDB / ID: 1cdc | ||||||
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Title | CD2, N-TERMINAL DOMAIN (1-99), TRUNCATED FORM | ||||||
Components | CD2 | ||||||
Keywords | IMMUNE SYSTEM PROTEIN / RECEPTOR / MISFOLDED / METASTABLE | ||||||
Function / homology | Function and homology information natural killer cell mediated cytotoxicity / natural killer cell activation / heterotypic cell-cell adhesion / positive regulation of interleukin-8 production / cytoplasmic side of plasma membrane / cell-cell adhesion / receptor tyrosine kinase binding / : / cell-cell junction / positive regulation of type II interferon production ...natural killer cell mediated cytotoxicity / natural killer cell activation / heterotypic cell-cell adhesion / positive regulation of interleukin-8 production / cytoplasmic side of plasma membrane / cell-cell adhesion / receptor tyrosine kinase binding / : / cell-cell junction / positive regulation of type II interferon production / positive regulation of tumor necrosis factor production / external side of plasma membrane / signaling receptor binding / protein kinase binding / Golgi apparatus / cell surface / protein-containing complex / extracellular region / nucleoplasm / identical protein binding / plasma membrane Similarity search - Function | ||||||
Biological species | Rattus norvegicus (Norway rat) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / Resolution: 2 Å | ||||||
Authors | Murray, A.J. / Barclay, A.N. / Brady, R.L. | ||||||
Citation | Journal: Proc.Natl.Acad.Sci.USA / Year: 1995 Title: One sequence, two folds: a metastable structure of CD2. Authors: Murray, A.J. / Lewis, S.J. / Barclay, A.N. / Brady, R.L. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1cdc.cif.gz | 50.7 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1cdc.ent.gz | 37.1 KB | Display | PDB format |
PDBx/mmJSON format | 1cdc.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/cd/1cdc ftp://data.pdbj.org/pub/pdb/validation_reports/cd/1cdc | HTTPS FTP |
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-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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Unit cell |
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-Components
#1: Protein | Mass: 11158.635 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Rattus norvegicus (Norway rat) / Description: PET / Plasmid: GST-FUSION / Production host: Escherichia coli (E. coli) / Strain (production host): PET / References: UniProt: P08921 #2: Water | ChemComp-HOH / | Source details | MOLECULE_NAME: CD2 (N-TERMINAL DOMAIN). EXPRESSED AS A GST-FUSION PROTEIN. | |
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-Experimental details
-Experiment
Experiment | Method: X-RAY DIFFRACTION |
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-Sample preparation
Crystal | Density Matthews: 2.16 Å3/Da / Density % sol: 43.14 % |
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Crystal grow | *PLUS pH: 7 / Method: vapor diffusion |
Components of the solutions | *PLUS Conc.: 2.5 M / Common name: ammonium sulfate |
-Data collection
Diffraction source | Source: SYNCHROTRON / Site: SRS / Beamline: PX9.6 / Wavelength: 0.88 |
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Detector | Type: MARRESEARCH / Detector: IMAGE PLATE / Date: May 22, 1994 |
Radiation | Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 0.88 Å / Relative weight: 1 |
Reflection | Resolution: 2→6 Å / Num. obs: 13465 / % possible obs: 99.3 % / Observed criterion σ(I): 0 / Redundancy: 3.8 % / Rmerge(I) obs: 0.065 |
Reflection | *PLUS Num. measured all: 51353 / Rmerge(I) obs: 0.065 |
-Processing
Software |
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Refinement | Resolution: 2→6 Å / σ(F): 0
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Displacement parameters | Biso mean: 20 Å2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement step | Cycle: LAST / Resolution: 2→6 Å
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Refine LS restraints |
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Refine LS restraints | *PLUS
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