登録情報 | データベース: PDB / ID: 7mrs |
---|
タイトル | Zebrafish CNTN4 APPb complex |
---|
要素 | - Amyloid-beta A4 protein
- Contactin-4
|
---|
キーワード | CELL ADHESION / Ig superfamily / amyloid precursor protein |
---|
機能・相同性 | 機能・相同性情報
convergent extension / regulation of Notch signaling pathway / cell-cell adhesion mediator activity / vasculature development / axon extension / regulation of neuron differentiation / Golgi-associated vesicle / transition metal ion binding / axonogenesis / central nervous system development ...convergent extension / regulation of Notch signaling pathway / cell-cell adhesion mediator activity / vasculature development / axon extension / regulation of neuron differentiation / Golgi-associated vesicle / transition metal ion binding / axonogenesis / central nervous system development / axon guidance / brain development / cell-cell adhesion / neuron projection development / heparin binding / membrane => GO:0016020 / axon / plasma membrane類似検索 - 分子機能 Amyloid-beta precursor protein / Amyloidogenic glycoprotein, copper-binding / Amyloidogenic glycoprotein, copper-binding domain conserved site / Amyloidogenic glycoprotein, copper-binding domain superfamily / Copper-binding of amyloid precursor, CuBD / Amyloid precursor protein (APP) copper-binding (CuBD) domain signature. / Amyloidogenic glycoprotein, amyloid-beta peptide superfamily / Beta-amyloid peptide (beta-APP) / Amyloidogenic glycoprotein, amyloid-beta peptide / Amyloid precursor protein (APP) E1 domain profile. ...Amyloid-beta precursor protein / Amyloidogenic glycoprotein, copper-binding / Amyloidogenic glycoprotein, copper-binding domain conserved site / Amyloidogenic glycoprotein, copper-binding domain superfamily / Copper-binding of amyloid precursor, CuBD / Amyloid precursor protein (APP) copper-binding (CuBD) domain signature. / Amyloidogenic glycoprotein, amyloid-beta peptide superfamily / Beta-amyloid peptide (beta-APP) / Amyloidogenic glycoprotein, amyloid-beta peptide / Amyloid precursor protein (APP) E1 domain profile. / Amyloid precursor protein (APP) E2 domain profile. / Amyloidogenic glycoprotein, extracellular / Amyloidogenic glycoprotein, heparin-binding / Amyloidogenic glycoprotein, E2 domain / E2 domain superfamily / Amyloidogenic glycoprotein, heparin-binding domain superfamily / Amyloid A4 N-terminal heparin-binding / E2 domain of amyloid precursor protein / amyloid A4 / Amyloidogenic glycoprotein / Immunoglobulin domain / Immunoglobulin I-set / Immunoglobulin I-set domain / Fibronectin type III domain / Fibronectin type 3 domain / Immunoglobulin subtype 2 / Immunoglobulin C-2 Type / Fibronectin type-III domain profile. / Fibronectin type III / Fibronectin type III superfamily / Immunoglobulin subtype / Immunoglobulin / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulin-like fold類似検索 - ドメイン・相同性 Amyloid-beta A4 protein / Contactin-4 precursor類似検索 - 構成要素 |
---|
生物種 | ![](img/tx_fish.gif) Danio rerio (ゼブラフィッシュ) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.93 Å |
---|
データ登録者 | Bouyain, S. / Karuppan, S.J. |
---|
資金援助 | 米国, 1件 組織 | 認可番号 | 国 |
---|
National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS) | 1R15NS108371-01 | 米国 |
|
---|
引用 | ジャーナル: J.Biol.Chem. / 年: 2021 タイトル: Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface. 著者: Karuppan, S.J. / Vogt, A. / Fischer, Z. / Ladutska, A. / Swiastyn, J. / McGraw, H.F. / Bouyain, S. |
---|
履歴 | 登録 | 2021年5月9日 | 登録サイト: RCSB / 処理サイト: RCSB |
---|
改定 1.0 | 2022年1月5日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2022年2月9日 | Group: Database references / カテゴリ: citation / Item: _citation.journal_volume |
---|
改定 1.2 | 2023年10月18日 | Group: Data collection / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
---|
|
---|