Entry | Database: PDB / ID: 7kl7 |
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Title | Helicobacter pylori Xanthine-Guanine-Hypoxanthine Phosphoribosyltransferase |
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Components | Phosphoribosyltransferase |
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Keywords | TRANSFERASE / Helicobacter pylori Xanthine-Guanine-Hypoxanthine Phosphoribosyltransferase Drug discovery Nucleoside phosphates |
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Function / homology | Phosphoribosyl transferase domain / Phosphoribosyltransferase-like / Phosphoribosyltransferase domain / glycosyltransferase activity / Phosphoribosyltransferase Function and homology information |
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Biological species | ![](img/tx_bacteria.gif) Helicobacter pylori (bacteria) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MIR / Resolution: 1.47 Å |
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Authors | Guddat, L.W. / Keough, D.T. |
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Funding support | Australia, 1items Organization | Grant number | Country |
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National Health and Medical Research Council (NHMRC, Australia) | | Australia |
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Citation | Journal: J.Med.Chem. / Year: 2021 Title: Helicobacter pylori Xanthine-Guanine-Hypoxanthine Phosphoribosyltransferase-A Putative Target for Drug Discovery against Gastrointestinal Tract Infections. Authors: Keough, D.T. / Wun, S.J. / Baszczynski, O. / Eng, W.S. / Spacek, P. / Panjikar, S. / Naesens, L. / Pohl, R. / Rejman, D. / Hockova, D. / Ferrero, R.L. / Guddat, L.W. |
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History | Deposition | Oct 29, 2020 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | May 5, 2021 | Provider: repository / Type: Initial release |
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Revision 1.1 | May 12, 2021 | Group: Refinement description / Category: software |
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Revision 1.2 | May 26, 2021 | Group: Database references / Category: citation / citation_author Item: _citation.journal_volume / _citation.page_first ..._citation.journal_volume / _citation.page_first / _citation.page_last / _citation_author.identifier_ORCID |
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Revision 1.3 | Mar 6, 2024 | Group: Data collection / Database references / Category: chem_comp_atom / chem_comp_bond / database_2 Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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