- PDB-7ckf: The N-terminus of interferon-inducible antiviral protein-dimer -
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Basic information
Entry
Database: PDB / ID: 7ckf
Title
The N-terminus of interferon-inducible antiviral protein-dimer
Components
Guanylate-binding protein 5
Keywords
HYDROLASE / antiviral
Function / homology
Function and homology information
positive regulation of AIM2 inflammasome complex assembly / symbiont cell surface / protein localization to Golgi apparatus / positive regulation of interleukin-18 production / cytolysis in another organism / positive regulation of pyroptotic inflammatory response / positive regulation of innate immune response / positive regulation of cytokine production involved in inflammatory response / positive regulation of NLRP3 inflammasome complex assembly / endopeptidase inhibitor activity ...positive regulation of AIM2 inflammasome complex assembly / symbiont cell surface / protein localization to Golgi apparatus / positive regulation of interleukin-18 production / cytolysis in another organism / positive regulation of pyroptotic inflammatory response / positive regulation of innate immune response / positive regulation of cytokine production involved in inflammatory response / positive regulation of NLRP3 inflammasome complex assembly / endopeptidase inhibitor activity / molecular function inhibitor activity / protein targeting / side of membrane / activation of innate immune response / positive regulation of interleukin-1 beta production / Hydrolases; Acting on acid anhydrides; Acting on GTP to facilitate cellular and subcellular movement / cytoplasmic vesicle membrane / cellular response to type II interferon / Interferon gamma signaling / cytoplasmic vesicle / cellular response to lipopolysaccharide / protein homotetramerization / defense response to virus / defense response to bacterium / inflammatory response / Golgi membrane / GTPase activity / GTP binding / perinuclear region of cytoplasm / Golgi apparatus / protein homodimerization activity / identical protein binding / membrane / cytoplasm Similarity search - Function
Guanylate-bindingprotein5 / interferon-induced antiviral protein / GBP-TA antigen / GTP-binding protein 5 / GBP-5 / Guanine ...interferon-induced antiviral protein / GBP-TA antigen / GTP-binding protein 5 / GBP-5 / Guanine nucleotide-binding protein 5
Mass: 35426.527 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / Gene: GBP5, UNQ2427/PRO4987 / Production host: Escherichia coli K-12 (bacteria) / Strain (production host): K-12 References: UniProt: Q96PP8, Hydrolases; Acting on acid anhydrides; Acting on GTP to facilitate cellular and subcellular movement
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