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- PDB-6yep: LNA modified G-quadruplex with flipped G-tract and central tetrad -
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Open data
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Basic information
Entry | Database: PDB / ID: 6yep | ||||||||||||||||||||||||||||
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Title | LNA modified G-quadruplex with flipped G-tract and central tetrad | ||||||||||||||||||||||||||||
![]() | DNA (5'-D(*![]() DNA / G-quadruplex / LNA / tetrad flip / G-tract flip | Function / homology | DNA / DNA (> 10) | ![]() Biological species | synthetic construct (others) | Method | SOLUTION NMR / simulated annealing / molecular dynamics | ![]() Weisz, K. / Haase, L. | Funding support | | ![]()
![]() ![]() Title: Locked nucleic acid building blocks as versatile tools for advanced G-quadruplex design. Authors: Haase, L. / Weisz, K. History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 144 KB | Display | ![]() |
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PDB format | ![]() | 116.4 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 326 KB | Display | ![]() |
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Full document | ![]() | 376.7 KB | Display | |
Data in XML | ![]() | 7.4 KB | Display | |
Data in CIF | ![]() | 11.2 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 6ycvC C: citing same article ( |
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Similar structure data | |
Other databases |
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Links
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Assembly
Deposited unit | ![]()
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NMR ensembles |
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Components
#1: DNA chain | Mass: 7000.501 Da / Num. of mol.: 1 / Source method: obtained synthetically / Source: (synth.) synthetic construct (others) |
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Has ligand of interest | N |
-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||||||||||||||||||
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NMR experiment |
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Sample preparation
Details |
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Sample |
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Sample conditions | Ionic strength: 15 mM / Label: 10mMKP-298K / pH: 7 / Pressure: 1 atm / Temperature: 298 K |
-NMR measurement
NMR spectrometer | Type: Bruker AVANCE NEO / Manufacturer: Bruker / Model: AVANCE NEO / Field strength: 600 MHz |
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Processing
NMR software |
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Refinement |
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NMR representative | Selection criteria: lowest energy | ||||||||||||||||||||||||
NMR ensemble | Conformer selection criteria: structures with the lowest energy Conformers calculated total number: 14 / Conformers submitted total number: 10 |