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Yorodumi- PDB-6q23: Crystal structure of human 1G01 Fab in complex with influenza vir... -
+Open data
-Basic information
Entry | Database: PDB / ID: 6q23 | ||||||
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Title | Crystal structure of human 1G01 Fab in complex with influenza virus neuraminidase from A/California/04/2009 (H1N1) | ||||||
Components |
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Keywords | VIRAL PROTEIN / HYDROLASE/IMMUNE SYSTEM / broadly protective human antibody / inhibition / active site / antibody-neuraminidase complex / HYDROLASE-IMMUNE SYSTEM complex | ||||||
Function / homology | Function and homology information exo-alpha-(2->3)-sialidase activity / exo-alpha-(2->6)-sialidase activity / exo-alpha-(2->8)-sialidase activity / exo-alpha-sialidase / viral budding from plasma membrane / membrane => GO:0016020 / carbohydrate metabolic process / host cell plasma membrane / virion membrane / identical protein binding ...exo-alpha-(2->3)-sialidase activity / exo-alpha-(2->6)-sialidase activity / exo-alpha-(2->8)-sialidase activity / exo-alpha-sialidase / viral budding from plasma membrane / membrane => GO:0016020 / carbohydrate metabolic process / host cell plasma membrane / virion membrane / identical protein binding / membrane / metal ion binding Similarity search - Function | ||||||
Biological species | Influenza A virus Homo sapiens (human) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.27 Å | ||||||
Authors | Zhu, X. / Wilson, I.A. | ||||||
Funding support | United States, 1items
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Citation | Journal: Science / Year: 2019 Title: Broadly protective human antibodies that target the active site of influenza virus neuraminidase. Authors: Stadlbauer, D. / Zhu, X. / McMahon, M. / Turner, J.S. / Wohlbold, T.J. / Schmitz, A.J. / Strohmeier, S. / Yu, W. / Nachbagauer, R. / Mudd, P.A. / Wilson, I.A. / Ellebedy, A.H. / Krammer, F. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 6q23.cif.gz | 633.9 KB | Display | PDBx/mmCIF format |
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PDB format | pdb6q23.ent.gz | 518.7 KB | Display | PDB format |
PDBx/mmJSON format | 6q23.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 6q23_validation.pdf.gz | 2.8 MB | Display | wwPDB validaton report |
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Full document | 6q23_full_validation.pdf.gz | 2.9 MB | Display | |
Data in XML | 6q23_validation.xml.gz | 109.9 KB | Display | |
Data in CIF | 6q23_validation.cif.gz | 150.6 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/q2/6q23 ftp://data.pdbj.org/pub/pdb/validation_reports/q2/6q23 | HTTPS FTP |
-Related structure data
Related structure data | 6q1zC 6q20C 3nssS 4fqlS 5itbS S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data |
-Links
-Assembly
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Component-ID: _ / Refine code: _
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