+Open data
-Basic information
Entry | Database: PDB / ID: 6i2y | ||||||
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Title | Human STK10 bound to Foretinib | ||||||
Components | Serine/threonine-protein kinase 10 | ||||||
Keywords | TRANSFERASE / kinase / inhibitor / complex / LOK / foretinib | ||||||
Function / homology | Function and homology information lymphocyte aggregation / regulation of lymphocyte migration / RHOB GTPase cycle / RHOC GTPase cycle / RHOA GTPase cycle / specific granule membrane / protein autophosphorylation / non-specific serine/threonine protein kinase / protein phosphorylation / protein serine kinase activity ...lymphocyte aggregation / regulation of lymphocyte migration / RHOB GTPase cycle / RHOC GTPase cycle / RHOA GTPase cycle / specific granule membrane / protein autophosphorylation / non-specific serine/threonine protein kinase / protein phosphorylation / protein serine kinase activity / protein serine/threonine kinase activity / Neutrophil degranulation / protein homodimerization activity / extracellular exosome / ATP binding / identical protein binding / plasma membrane / cytoplasm / cytosol Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.56 Å | ||||||
Authors | Sorrell, F.J. / Berger, B.-T. / Oerum, S. / von Delft, F. / Bountra, C. / Arrowsmith, C. / Edwards, A.M. / Knapp, S. / Elkins, J.M. | ||||||
Citation | Journal: To Be Published Title: Human STK10 bound to GW683134 Authors: Sorrell, F.J. / Elkins, J.M. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 6i2y.cif.gz | 222.7 KB | Display | PDBx/mmCIF format |
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PDB format | pdb6i2y.ent.gz | 186.9 KB | Display | PDB format |
PDBx/mmJSON format | 6i2y.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 6i2y_validation.pdf.gz | 884.3 KB | Display | wwPDB validaton report |
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Full document | 6i2y_full_validation.pdf.gz | 890.8 KB | Display | |
Data in XML | 6i2y_validation.xml.gz | 21.5 KB | Display | |
Data in CIF | 6i2y_validation.cif.gz | 28.2 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/i2/6i2y ftp://data.pdbj.org/pub/pdb/validation_reports/i2/6i2y | HTTPS FTP |
-Related structure data
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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