Entry Database : PDB / ID : 5mp7 Structure visualization Downloads & linksTitle Crystal structure of phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis ComponentsRibose-phosphate pyrophosphokinase Details Keywords TRANSFERASE / phosphoribosylpyrophosphate synthetase / PRPP synthetase / Mycobacterium smegmatisFunction / homology Function and homology informationFunction Domain/homology Component
ribose-phosphate diphosphokinase / ribose phosphate diphosphokinase activity / ribonucleoside monophosphate biosynthetic process / nucleotide biosynthetic process / 5-phosphoribose 1-diphosphate biosynthetic process / nucleoside metabolic process / kinase activity / magnesium ion binding / ATP binding / cytoplasm Similarity search - Function Phosphoribosyl pyrophosphate synthetase, conserved site / Phosphoribosyl pyrophosphate synthase signature. / Ribose-phosphate pyrophosphokinase, bacterial-type / Phosphoribosyl synthetase-associated domain / Ribose-phosphate pyrophosphokinase / Ribose-phosphate pyrophosphokinase, N-terminal domain / N-terminal domain of ribose phosphate pyrophosphokinase / Rossmann fold - #2020 / Phosphoribosyltransferase-like / Phosphoribosyltransferase domain ... Phosphoribosyl pyrophosphate synthetase, conserved site / Phosphoribosyl pyrophosphate synthase signature. / Ribose-phosphate pyrophosphokinase, bacterial-type / Phosphoribosyl synthetase-associated domain / Ribose-phosphate pyrophosphokinase / Ribose-phosphate pyrophosphokinase, N-terminal domain / N-terminal domain of ribose phosphate pyrophosphokinase / Rossmann fold - #2020 / Phosphoribosyltransferase-like / Phosphoribosyltransferase domain / Rossmann fold / 3-Layer(aba) Sandwich / Alpha Beta Similarity search - Domain/homologyBiological species Mycobacterium smegmatis (bacteria)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.4 Å DetailsAuthors Donini, S. / Garavaglia, S. / Ferraris, D.M. / Miggiano, R. / Mori, S. / Shibayama, K. / Rizzi, M. Funding support Italy, 1items Details Hide detailsOrganization Grant number Country EU 7th Framework Program 260872 Italy
CitationJournal : PLoS ONE / Year : 2017Title : Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis.Authors : Donini, S. / Garavaglia, S. / Ferraris, D.M. / Miggiano, R. / Mori, S. / Shibayama, K. / Rizzi, M. History Deposition Dec 16, 2016 Deposition site : PDBE / Processing site : PDBERevision 1.0 Apr 26, 2017 Provider : repository / Type : Initial releaseRevision 1.1 Feb 20, 2019 Group : Advisory / Data collection / Derived calculationsCategory : pdbx_data_processing_status / pdbx_validate_close_contact ... pdbx_data_processing_status / pdbx_validate_close_contact / struct_conn / struct_conn_type Revision 1.2 Jul 13, 2022 Group : Database references / Structure summary / Category : audit_author / database_2Item : _audit_author.name / _database_2.pdbx_DOI / _database_2.pdbx_database_accessionRevision 1.3 Jan 17, 2024 Group : Data collection / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model / struct_ncs_dom_lim Item : _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id ... _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id
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