登録情報 データベース : PDB / ID : 5j31 構造の表示 ダウンロードとリンクタイトル Crystal structure of 14-3-3zeta in complex with an alkyne cross-linked cyclic peptide derived from ExoS 要素14-3-3 protein zeta/delta Exoenzyme S 詳細キーワード SIGNALING PROTEIN / constrained peptides / protein-protein-interaction / alkyne cross-link / 14-3-3 protein zeta機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
Golgi reassembly / synaptic target recognition / respiratory system process / NOTCH4 Activation and Transmission of Signal to the Nucleus / establishment of Golgi localization / regulation of synapse maturation / tube formation / Rap1 signalling / negative regulation of protein localization to nucleus / KSRP (KHSRP) binds and destabilizes mRNA ... Golgi reassembly / synaptic target recognition / respiratory system process / NOTCH4 Activation and Transmission of Signal to the Nucleus / establishment of Golgi localization / regulation of synapse maturation / tube formation / Rap1 signalling / negative regulation of protein localization to nucleus / KSRP (KHSRP) binds and destabilizes mRNA / GP1b-IX-V activation signalling / Regulation of localization of FOXO transcription factors / NAD+-protein poly-ADP-ribosyltransferase activity / phosphoserine residue binding / Interleukin-3, Interleukin-5 and GM-CSF signaling / Activation of BAD and translocation to mitochondria / protein targeting / SARS-CoV-2 targets host intracellular signalling and regulatory pathways / Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex / cellular response to glucose starvation / SARS-CoV-1 targets host intracellular signalling and regulatory pathways / RHO GTPases activate PKNs / negative regulation of TORC1 signaling / protein sequestering activity / ERK1 and ERK2 cascade / negative regulation of innate immune response / nucleotidyltransferase activity / hippocampal mossy fiber to CA3 synapse / GTPase activator activity / regulation of ERK1 and ERK2 cascade / Translocation of SLC2A4 (GLUT4) to the plasma membrane / Deactivation of the beta-catenin transactivating complex / TP53 Regulates Metabolic Genes / Negative regulation of NOTCH4 signaling / lung development / regulation of protein stability / protein localization / melanosome / toxin activity / angiogenesis / DNA-binding transcription factor binding / vesicle / transmembrane transporter binding / blood microparticle / cadherin binding / protein domain specific binding / protein phosphorylation / focal adhesion / glutamatergic synapse / ubiquitin protein ligase binding / negative regulation of apoptotic process / protein kinase binding / negative regulation of transcription by RNA polymerase II / signal transduction / RNA binding / extracellular space / extracellular exosome / extracellular region / nucleoplasm / identical protein binding / nucleus / cytosol / cytoplasm 類似検索 - 分子機能 Type III secretion system effector protein YopE-like / Virulence factor YopE, GAP domain / Virulence factor YopE, GAP domain superfamily / : / Yersinia virulence determinant (YopE) / ADP ribosyltransferase / ADP-ribosyltransferase exoenzyme / Toxin-related mono-ADP-ribosyltransferase (TR mART) core domain profile. / 14-3-3 domain / Delta-Endotoxin; domain 1 ... Type III secretion system effector protein YopE-like / Virulence factor YopE, GAP domain / Virulence factor YopE, GAP domain superfamily / : / Yersinia virulence determinant (YopE) / ADP ribosyltransferase / ADP-ribosyltransferase exoenzyme / Toxin-related mono-ADP-ribosyltransferase (TR mART) core domain profile. / 14-3-3 domain / Delta-Endotoxin; domain 1 / 14-3-3 proteins signature 2. / 14-3-3 protein, conserved site / 14-3-3 proteins signature 1. / 14-3-3 protein / 14-3-3 homologues / 14-3-3 domain / 14-3-3 domain superfamily / 14-3-3 protein / Up-down Bundle / Mainly Alpha 類似検索 - ドメイン・相同性 BENZOIC ACID / 14-3-3 protein zeta/delta / Exoenzyme S 類似検索 - 構成要素生物種 Homo sapiens (ヒト)Pseudomonas aeruginosa (緑膿菌)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.4 Å 詳細データ登録者 Wallraven, K. / Cromm, P. / Bier, D. / Glas, A. / Grossmann, T. 引用ジャーナル : Chembiochem / 年 : 2016タイトル : Constraining an Irregular Peptide Secondary Structure through Ring-Closing Alkyne Metathesis.著者 : Cromm, P.M. / Wallraven, K. / Glas, A. / Bier, D. / Furstner, A. / Ottmann, C. / Grossmann, T.N. 履歴 登録 2016年3月30日 登録サイト : RCSB / 処理サイト : PDBE改定 1.0 2016年10月19日 Provider : repository / タイプ : Initial release改定 1.1 2016年10月26日 Group : Database references改定 1.2 2024年1月10日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_conn Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_leaving_atom_flag
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