登録情報 | データベース: PDB / ID: 5fc8 |
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タイトル | Mouse importin alpha: Dengue 3 NS5 C-terminal NLS peptide complex |
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要素 | - Importin subunit alpha-1
- Nonstructural protein 5
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キーワード | PROTEIN TRANSPORT/Viral Protein / Dengue / NS5 / Importin / PROTEIN TRANSPORT-Viral Protein complex |
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機能・相同性 | 機能・相同性情報
Sensing of DNA Double Strand Breaks / entry of viral genome into host nucleus through nuclear pore complex via importin / positive regulation of viral life cycle / NLS-dependent protein nuclear import complex / postsynapse to nucleus signaling pathway / nuclear import signal receptor activity / cytoplasmic stress granule / protein import into nucleus / host cell / DNA-binding transcription factor binding ...Sensing of DNA Double Strand Breaks / entry of viral genome into host nucleus through nuclear pore complex via importin / positive regulation of viral life cycle / NLS-dependent protein nuclear import complex / postsynapse to nucleus signaling pathway / nuclear import signal receptor activity / cytoplasmic stress granule / protein import into nucleus / host cell / DNA-binding transcription factor binding / postsynaptic density / RNA-directed RNA polymerase activity / glutamatergic synapse / nucleoplasm / cytosol類似検索 - 分子機能 Importin subunit alpha / Atypical Arm repeat / Importin-alpha, importin-beta-binding domain superfamily / Importin beta binding domain / Atypical Arm repeat / Importin-alpha, importin-beta-binding domain / IBB domain profile. / Armadillo/plakoglobin ARM repeat profile. / Armadillo/beta-catenin-like repeat / Armadillo/beta-catenin-like repeats ...Importin subunit alpha / Atypical Arm repeat / Importin-alpha, importin-beta-binding domain superfamily / Importin beta binding domain / Atypical Arm repeat / Importin-alpha, importin-beta-binding domain / IBB domain profile. / Armadillo/plakoglobin ARM repeat profile. / Armadillo/beta-catenin-like repeat / Armadillo/beta-catenin-like repeats / Armadillo / Leucine-rich Repeat Variant / Leucine-rich Repeat Variant / RNA-directed RNA polymerase, thumb domain, Flavivirus / Flavivirus RNA-directed RNA polymerase, thumb domain / Armadillo-like helical / Alpha Horseshoe / Armadillo-type fold / DNA/RNA polymerase superfamily / Mainly Alpha類似検索 - ドメイン・相同性 Nonstructural protein 5 / Importin subunit alpha-1類似検索 - 構成要素 |
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生物種 | Dengue virus 3 (デング熱ウイルス)
 Mus musculus (ハツカネズミ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.1 Å |
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データ登録者 | Smith, K.M. / Forwood, J.K. |
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引用 | ジャーナル: PLoS Pathog. / 年: 2016 タイトル: The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production. 著者: Tay, M.Y. / Smith, K. / Ng, I.H. / Chan, K.W. / Zhao, Y. / Ooi, E.E. / Lescar, J. / Luo, D. / Jans, D.A. / Forwood, J.K. / Vasudevan, S.G. |
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履歴 | 登録 | 2015年12月15日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2016年5月18日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2016年7月20日 | Group: Data collection |
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改定 1.2 | 2017年11月22日 | Group: Data collection / Derived calculations / Refinement description カテゴリ: diffrn_source / pdbx_struct_oper_list / software Item: _diffrn_source.pdbx_synchrotron_site / _pdbx_struct_oper_list.symmetry_operation |
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改定 1.3 | 2019年2月13日 | Group: Data collection / Database references / カテゴリ: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
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改定 1.4 | 2023年9月27日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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