Entry | Database: PDB / ID: 5ept |
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Title | Crystal Structure of S. cerevisiae TSA2 in the disulfide state |
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Components | Peroxiredoxin TSA2 |
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Keywords | OXIDOREDUCTASE / Peroxiredoxin / Peroxidase / Oxidative Stress |
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Function / homology | Function and homology information
TP53 Regulates Metabolic Genes / Detoxification of Reactive Oxygen Species / thioredoxin-dependent peroxiredoxin / peroxiredoxin activity / thioredoxin peroxidase activity / Neutrophil degranulation / removal of superoxide radicals / cell redox homeostasis / hydrogen peroxide catabolic process / protein folding ...TP53 Regulates Metabolic Genes / Detoxification of Reactive Oxygen Species / thioredoxin-dependent peroxiredoxin / peroxiredoxin activity / thioredoxin peroxidase activity / Neutrophil degranulation / removal of superoxide radicals / cell redox homeostasis / hydrogen peroxide catabolic process / protein folding / cellular response to oxidative stress / response to oxidative stress / protein stabilization / cytoplasm / cytosolSimilarity search - Function Peroxiredoxin, AhpC-type / Peroxiredoxin, C-terminal / C-terminal domain of 1-Cys peroxiredoxin / Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant / AhpC/TSA family / Thioredoxin domain profile. / Thioredoxin domain / Thioredoxin-like superfamilySimilarity search - Domain/homology |
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Biological species | ![](img/tx_yeast.gif) Saccharomyces cerevisiae (brewer's yeast) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 5 Å |
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Authors | Nielsen, M.H. / Kidmose, R.T. / Jenner, L.B. |
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Citation | Journal: Acta Crystallogr D Struct Biol / Year: 2016 Title: Structure of TSA2 reveals novel features of the active-site loop of peroxiredoxins. Authors: Nielsen, M.H. / Kidmose, R.T. / Jenner, L.B. |
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History | Deposition | Nov 12, 2015 | Deposition site: RCSB / Processing site: PDBE |
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Revision 1.0 | Jan 13, 2016 | Provider: repository / Type: Initial release |
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Revision 1.1 | Mar 2, 2016 | Group: Database references |
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Revision 1.2 | Feb 20, 2019 | Group: Advisory / Data collection / Derived calculations Category: pdbx_data_processing_status / pdbx_validate_close_contact ...pdbx_data_processing_status / pdbx_validate_close_contact / struct_conn / struct_conn_type |
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Revision 1.3 | Jan 10, 2024 | Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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