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Yorodumi- PDB-5ayz: CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE ... -
+Open data
-Basic information
Entry | Database: PDB / ID: 5ayz | |||||||||
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Title | CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE PRODUCT NICOTINATE MONONUCLEOTIDE | |||||||||
Components | Nicotinate-nucleotide pyrophosphorylase [carboxylating] | |||||||||
Keywords | TRANSFERASE | |||||||||
Function / homology | Function and homology information quinolinate catabolic process / nicotinate-nucleotide diphosphorylase (carboxylating) / nicotinate-nucleotide diphosphorylase (carboxylating) activity / Nicotinate metabolism / NAD metabolic process / NAD biosynthetic process / catalytic complex / extracellular exosome / identical protein binding / cytosol / cytoplasm Similarity search - Function | |||||||||
Biological species | Homo sapiens (human) | |||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.6 Å | |||||||||
Authors | Youn, H.S. / Kim, T.G. / Kim, M.K. / Kang, G.B. / Kang, J.Y. / Seo, Y.J. / Lee, J.G. / An, J.Y. / Park, K.R. / Lee, Y. ...Youn, H.S. / Kim, T.G. / Kim, M.K. / Kang, G.B. / Kang, J.Y. / Seo, Y.J. / Lee, J.G. / An, J.Y. / Park, K.R. / Lee, Y. / Im, Y.J. / Lee, J.H. / Fukuoka, S.I. / Eom, S.H. | |||||||||
Citation | Journal: Sci Rep / Year: 2016 Title: Structural Insights into the Quaternary Catalytic Mechanism of Hexameric Human Quinolinate Phosphoribosyltransferase, a Key Enzyme in de novo NAD Biosynthesis Authors: Youn, H.S. / Kim, T.G. / Kim, M.K. / Kang, G.B. / Kang, J.Y. / Lee, J.G. / An, J.Y. / Park, K.R. / Lee, Y. / Im, Y.J. / Lee, J.H. / Eom, S.H. | |||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 5ayz.cif.gz | 626.9 KB | Display | PDBx/mmCIF format |
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PDB format | pdb5ayz.ent.gz | 516.4 KB | Display | PDB format |
PDBx/mmJSON format | 5ayz.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/ay/5ayz ftp://data.pdbj.org/pub/pdb/validation_reports/ay/5ayz | HTTPS FTP |
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-Related structure data
Related structure data | 5ayxC 5ayyC 3lar C: citing same article (ref.) S: Starting model for refinement |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
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