登録情報 | データベース: PDB / ID: 4ynz |
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タイトル | Structure of the N-terminal domain of SAD |
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要素 | Serine/threonine-protein kinase BRSK2 |
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キーワード | TRANSFERASE / kinase domain / UBA domain |
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機能・相同性 | 機能・相同性情報
distal axon / microtubule cytoskeleton organization involved in establishment of planar polarity / : / regulation of insulin secretion involved in cellular response to glucose stimulus / tau-protein kinase / establishment of cell polarity / tau-protein kinase activity / regulation of axonogenesis / regulation of neuron projection development / exocytosis ...distal axon / microtubule cytoskeleton organization involved in establishment of planar polarity / : / regulation of insulin secretion involved in cellular response to glucose stimulus / tau-protein kinase / establishment of cell polarity / tau-protein kinase activity / regulation of axonogenesis / regulation of neuron projection development / exocytosis / intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress / ERAD pathway / axonogenesis / neuron projection morphogenesis / neuron differentiation / G2/M transition of mitotic cell cycle / ATPase binding / peptidyl-serine phosphorylation / non-specific serine/threonine protein kinase / intracellular signal transduction / cell division / protein phosphorylation / protein serine kinase activity / protein serine/threonine kinase activity / centrosome / protein kinase binding / perinuclear region of cytoplasm / magnesium ion binding / endoplasmic reticulum / ATP binding / cytoplasm類似検索 - 分子機能 Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Phosphorylase Kinase; domain 1 / Phosphorylase Kinase; domain 1 / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. ...Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Phosphorylase Kinase; domain 1 / Phosphorylase Kinase; domain 1 / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / 2-Layer Sandwich / Orthogonal Bundle / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | ![](img/tx_mammal.gif) Mus musculus (ハツカネズミ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2 Å |
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データ登録者 | Wu, J.X. / Wang, J. / Chen, L. / Wang, Z.X. / Wu, J.W. |
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資金援助 | 中国, 4件 組織 | 認可番号 | 国 |
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National Natural Science Foundation of China | 31130062 | 中国 | National Natural Science Foundation of China | 31321003 | 中国 | Ministry of Science and Technology | 2011CB910800 | 中国 | Ministry of Science and Technology | 2013CB530600 | 中国 |
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引用 | ジャーナル: Nat Commun / 年: 2015 タイトル: Structural insight into the mechanism of synergistic autoinhibition of SAD kinases 著者: Wu, J.X. / Cheng, Y.S. / Wang, J. / Chen, L. / Ding, M. / Wu, J.W. |
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履歴 | 登録 | 2015年3月11日 | 登録サイト: RCSB / 処理サイト: PDBJ |
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改定 1.0 | 2015年12月16日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2017年10月18日 | Group: Author supporting evidence / Derived calculations / カテゴリ: pdbx_audit_support / pdbx_struct_oper_list Item: _pdbx_audit_support.funding_organization / _pdbx_struct_oper_list.symmetry_operation |
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改定 1.2 | 2023年11月8日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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