登録情報 データベース : PDB / ID : 4nrt 構造の表示 ダウンロードとリンクタイトル Human Norovirus polymerase bound to Compound 6 (suramin derivative) 要素hNV-RdRp 詳細 キーワード VIRAL PROTEIN/TRANSCRIPTION INHIBITOR / RNA dependent RNA Polymerase / VIRAL PROTEIN-TRANSCRIPTION INHIBITOR complex機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
calicivirin / RNA-protein covalent cross-linking / nucleoside-triphosphate phosphatase / RNA helicase activity / RNA-directed RNA polymerase / viral RNA genome replication / cysteine-type endopeptidase activity / RNA-dependent RNA polymerase activity / DNA-templated transcription / RNA binding / ATP binding 類似検索 - 分子機能 Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #3230 / Viral polyprotein, Caliciviridae N-terminal / Viral polyprotein N-terminal / Norovirus 3C-like protease (NV 3CLpro) domain profile. / Norovirus peptidase C37 / Southampton virus-type processing peptidase / Mitochondrial Import Receptor Subunit Tom20; Chain A - #20 / Mitochondrial Import Receptor Subunit Tom20; Chain A / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Reverse transcriptase/Diguanylate cyclase domain ... Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #3230 / Viral polyprotein, Caliciviridae N-terminal / Viral polyprotein N-terminal / Norovirus 3C-like protease (NV 3CLpro) domain profile. / Norovirus peptidase C37 / Southampton virus-type processing peptidase / Mitochondrial Import Receptor Subunit Tom20; Chain A - #20 / Mitochondrial Import Receptor Subunit Tom20; Chain A / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Reverse transcriptase/Diguanylate cyclase domain / Helicase, superfamily 3, single-stranded RNA virus / Superfamily 3 helicase of positive ssRNA viruses domain profile. / Helicase, superfamily 3, single-stranded DNA/RNA virus / RNA helicase / Helix non-globular / Special / RNA-directed RNA polymerase, C-terminal domain / Viral RNA-dependent RNA polymerase / Reverse transcriptase/Diguanylate cyclase domain / Alpha-Beta Plaits / RNA-directed RNA polymerase, catalytic domain / RdRp of positive ssRNA viruses catalytic domain profile. / ATPases associated with a variety of cellular activities / AAA+ ATPase domain / Peptidase S1, PA clan, chymotrypsin-like fold / Peptidase S1, PA clan / DNA/RNA polymerase superfamily / Up-down Bundle / P-loop containing nucleoside triphosphate hydrolase / 2-Layer Sandwich / Mainly Alpha / Alpha Beta 類似検索 - ドメイン・相同性生物種 Norwalk-like virus (ウイルス)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.022 Å 詳細データ登録者 Croci, R. / Pezzullo, M. / Tarantino, D. / Mastrangelo, E. / Milani, M. / Bolognesi, M. 引用ジャーナル : Plos One / 年 : 2014タイトル : Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds.著者 : Croci, R. / Pezzullo, M. / Tarantino, D. / Milani, M. / Tsay, S.C. / Sureshbabu, R. / Tsai, Y.J. / Mastrangelo, E. / Rohayem, J. / Bolognesi, M. / Hwu, J.R. 履歴 登録 2013年11月27日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2014年10月15日 Provider : repository / タイプ : Initial release改定 1.1 2023年9月20日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ref_seq_dif / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
すべて表示 表示を減らす