登録情報 | データベース: PDB / ID: 4jwy |
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タイトル | GluN2D ligand-binding core in complex with propyl-NHP5G |
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要素 | Glutamate receptor ionotropic, NMDA 2D |
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キーワード | TRANSPORT PROTEIN / bilobed structure / ion channel |
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機能・相同性 | 機能・相同性情報
regulation of sensory perception of pain / cellular response to L-glutamate / Assembly and cell surface presentation of NMDA receptors / voltage-gated monoatomic cation channel activity / regulation of monoatomic cation transmembrane transport / NMDA glutamate receptor activity / Synaptic adhesion-like molecules / NMDA selective glutamate receptor complex / RAF/MAP kinase cascade / calcium ion transmembrane import into cytosol ...regulation of sensory perception of pain / cellular response to L-glutamate / Assembly and cell surface presentation of NMDA receptors / voltage-gated monoatomic cation channel activity / regulation of monoatomic cation transmembrane transport / NMDA glutamate receptor activity / Synaptic adhesion-like molecules / NMDA selective glutamate receptor complex / RAF/MAP kinase cascade / calcium ion transmembrane import into cytosol / glutamate binding / startle response / regulation of neuronal synaptic plasticity / monoatomic cation transmembrane transport / positive regulation of excitatory postsynaptic potential / ionotropic glutamate receptor complex / Unblocking of NMDA receptors, glutamate binding and activation / monoatomic cation channel activity / glutamate-gated receptor activity / glutamate-gated calcium ion channel activity / presynaptic active zone membrane / ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential / ionotropic glutamate receptor signaling pathway / hippocampal mossy fiber to CA3 synapse / positive regulation of synaptic transmission, glutamatergic / adult locomotory behavior / excitatory postsynaptic potential / transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential / synaptic transmission, glutamatergic / long-term synaptic potentiation / postsynaptic density membrane / postsynaptic membrane / glutamatergic synapse / synapse / endoplasmic reticulum membrane / plasma membrane類似検索 - 分子機能 Bacterial extracellular solute-binding proteins, family 3 / Solute-binding protein family 3/N-terminal domain of MltF / Ionotropic glutamate receptor, metazoa / Ligated ion channel L-glutamate- and glycine-binding site / : / Ligand-gated ion channel / Ionotropic glutamate receptor, L-glutamate and glycine-binding domain / Ligated ion channel L-glutamate- and glycine-binding site / Ionotropic glutamate receptor / Eukaryotic homologues of bacterial periplasmic substrate binding proteins. ...Bacterial extracellular solute-binding proteins, family 3 / Solute-binding protein family 3/N-terminal domain of MltF / Ionotropic glutamate receptor, metazoa / Ligated ion channel L-glutamate- and glycine-binding site / : / Ligand-gated ion channel / Ionotropic glutamate receptor, L-glutamate and glycine-binding domain / Ligated ion channel L-glutamate- and glycine-binding site / Ionotropic glutamate receptor / Eukaryotic homologues of bacterial periplasmic substrate binding proteins. / Receptor, ligand binding region / Receptor family ligand binding region / Periplasmic binding protein-like II / Periplasmic binding protein-like I / D-Maltodextrin-Binding Protein; domain 2 / 3-Layer(aba) Sandwich / Alpha Beta類似検索 - ドメイン・相同性 Chem-1N4 / Glutamate receptor ionotropic, NMDA 2D類似検索 - 構成要素 |
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生物種 | ![](img/tx_mammal.gif) Rattus norvegicus (ドブネズミ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2 Å |
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データ登録者 | Hansen, K.B. / Tajima, N. / Risgaard, R. / Perszyk, R.E. / Jorgensen, L. / Vance, K.M. / Ogden, K.K. / Clausen, R.P. / Furukawa, H. / Traynelis, S.F. |
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引用 | ジャーナル: Mol.Pharmacol. / 年: 2013 タイトル: Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-d-aspartate receptors. 著者: Hansen, K.B. / Tajima, N. / Risgaard, R. / Perszyk, R.E. / Jorgensen, L. / Vance, K.M. / Ogden, K.K. / Clausen, R.P. / Furukawa, H. / Traynelis, S.F. |
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履歴 | 登録 | 2013年3月27日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2013年5月29日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2013年7月17日 | Group: Database references |
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改定 1.2 | 2017年8月2日 | Group: Advisory / Refinement description / Source and taxonomy カテゴリ: entity_src_gen / pdbx_unobs_or_zero_occ_atoms ...entity_src_gen / pdbx_unobs_or_zero_occ_atoms / pdbx_unobs_or_zero_occ_residues / software |
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改定 1.3 | 2023年9月20日 | Group: Advisory / Data collection ...Advisory / Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_unobs_or_zero_occ_atoms / pdbx_unobs_or_zero_occ_residues / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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