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- PDB-4c5g: Crystal structure of the minimal Pho-Sfmbt complex (P6122 spacegroup) -
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Open data
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Basic information
Entry | Database: PDB / ID: 4c5g | ||||||
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Title | Crystal structure of the minimal Pho-Sfmbt complex (P6122 spacegroup) | ||||||
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![]() | TRANSCRIPTION | ||||||
Function / homology | ![]() Transcriptional Regulation by E2F6 / polytene chromosome puff / imaginal disc growth / DNA Damage Recognition in GG-NER / SUMOylation of chromatin organization proteins / Estrogen-dependent gene expression / UCH proteinases / polytene chromosome / PcG protein complex / Ino80 complex ...Transcriptional Regulation by E2F6 / polytene chromosome puff / imaginal disc growth / DNA Damage Recognition in GG-NER / SUMOylation of chromatin organization proteins / Estrogen-dependent gene expression / UCH proteinases / polytene chromosome / PcG protein complex / Ino80 complex / dendrite morphogenesis / anterior/posterior axis specification / oogenesis / DNA topological change / heterochromatin formation / transcription initiation-coupled chromatin remodeling / methylated histone binding / chromatin DNA binding / DNA recombination / transcription regulator complex / sequence-specific DNA binding / DNA-binding transcription factor activity, RNA polymerase II-specific / chromatin remodeling / RNA polymerase II cis-regulatory region sequence-specific DNA binding / negative regulation of gene expression / DNA repair / negative regulation of DNA-templated transcription / chromatin binding / regulation of DNA-templated transcription / chromatin / regulation of transcription by RNA polymerase II / DNA binding / zinc ion binding / nucleus / metal ion binding Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Alfieri, C. / Glatt, S. / Mueller, C.W. | ||||||
![]() | ![]() Title: Structural Basis for Targeting the Chromatin Repressor Sfmbt to Polycomb Response Elements Authors: Alfieri, C. / Gambetta, M.C. / Matos, R. / Glatt, S. / Sehr, P. / Fraterman, S. / Wilm, M. / Mueller, J. / Mueller, C.W. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 205.7 KB | Display | ![]() |
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PDB format | ![]() | 164.2 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 431.5 KB | Display | ![]() |
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Full document | ![]() | 433.8 KB | Display | |
Data in XML | ![]() | 21 KB | Display | |
Data in CIF | ![]() | 30.8 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 4c5eC ![]() 4c5hC ![]() 4c5iC ![]() 3h6zS C: citing same article ( S: Starting model for refinement |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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Unit cell |
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Components
#1: Protein | Mass: 51067.664 Da / Num. of mol.: 1 / Fragment: 4MBT, RESIDUES 531-980 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() |
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#2: Protein/peptide | Mass: 3630.202 Da / Num. of mol.: 1 / Fragment: SPACER, RESIDUES 145-172 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() |
#3: Water | ChemComp-HOH / |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 3.2 Å3/Da / Density % sol: 58.8 % / Description: NONE |
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-Data collection
Diffraction | Mean temperature: 100 K |
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Diffraction source | Source: ![]() ![]() ![]() |
Detector | Type: ADSC QUANTUM 315r / Detector: CCD / Date: Jun 17, 2011 |
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 0.93927 Å / Relative weight: 1 |
Reflection | Resolution: 2.1→50 Å / Num. obs: 41850 / % possible obs: 99.5 % / Observed criterion σ(I): 1.5 / Redundancy: 15.6 % / Rmerge(I) obs: 0.16 / Net I/σ(I): 17.4 |
Reflection shell | Resolution: 2.1→2.15 Å / Redundancy: 15 % / Mean I/σ(I) obs: 1.5 / % possible all: 98.2 |
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Processing
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Refinement | Method to determine structure: ![]() Starting model: PDB ENRTY 3H6Z Resolution: 2.1→47.2 Å / SU ML: 0.27 / σ(F): 1.36 / Phase error: 28.48 / Stereochemistry target values: ML
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Solvent computation | Shrinkage radii: 0.9 Å / VDW probe radii: 1.11 Å / Solvent model: FLAT BULK SOLVENT MODEL | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement step | Cycle: LAST / Resolution: 2.1→47.2 Å
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Refine LS restraints |
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LS refinement shell |
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Refinement TLS params. | Method: refined / Refine-ID: X-RAY DIFFRACTION
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Refinement TLS group |
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