登録情報 データベース : PDB / ID : 3mng 構造の表示 ダウンロードとリンクタイトル wild type human PrxV with DTT bound as a competitive inhibitor 要素Peroxiredoxin-5, mitochondrial 詳細 キーワード OXIDOREDUCTASE / peroxiredoxin / peroxidase / PrxV / substrate analog / DTT機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
peroxynitrite reductase activity / reactive nitrogen species metabolic process / negative regulation of transcription by RNA polymerase III / negative regulation of oxidoreductase activity / NADPH oxidation / regulation of apoptosis involved in tissue homeostasis / RNA polymerase III transcription regulatory region sequence-specific DNA binding / thioredoxin-dependent peroxiredoxin / thioredoxin peroxidase activity / Detoxification of Reactive Oxygen Species ... peroxynitrite reductase activity / reactive nitrogen species metabolic process / negative regulation of transcription by RNA polymerase III / negative regulation of oxidoreductase activity / NADPH oxidation / regulation of apoptosis involved in tissue homeostasis / RNA polymerase III transcription regulatory region sequence-specific DNA binding / thioredoxin-dependent peroxiredoxin / thioredoxin peroxidase activity / Detoxification of Reactive Oxygen Species / antioxidant activity / cysteine-type endopeptidase inhibitor activity involved in apoptotic process / peroxisomal matrix / positive regulation of collagen biosynthetic process / cell redox homeostasis / hydrogen peroxide catabolic process / TP53 Regulates Metabolic Genes / cellular response to reactive oxygen species / peroxidase activity / peroxisome / cellular response to oxidative stress / cytoplasmic vesicle / response to oxidative stress / mitochondrial matrix / inflammatory response / intracellular membrane-bounded organelle / signaling receptor binding / negative regulation of apoptotic process / perinuclear region of cytoplasm / mitochondrion / extracellular space / extracellular exosome / identical protein binding / nucleus / cytoplasm / cytosol 類似検索 - 分子機能 Peroxiredoxin-5-like / Redoxin / Redoxin / Thioredoxin domain profile. / Thioredoxin domain / Glutaredoxin / Glutaredoxin / Thioredoxin-like superfamily / 3-Layer(aba) Sandwich / Alpha Beta 類似検索 - ドメイン・相同性 BROMIDE ION / (4S,5S)-1,2-DITHIANE-4,5-DIOL / Peroxiredoxin-5, mitochondrial 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / Rigid body refinement of starting model / 解像度 : 1.45 Å 詳細データ登録者 Hall, A. / Karplus, P.A. 引用ジャーナル : J.Mol.Biol. / 年 : 2010タイトル : Structural Evidence that Peroxiredoxin Catalytic Power Is Based on Transition-State Stabilization.著者 : Hall, A. / Parsonage, D. / Poole, L.B. / Karplus, P.A. 履歴 登録 2010年4月21日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2010年8月4日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Version format compliance改定 1.2 2023年9月6日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ref_seq_dif / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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