登録情報 データベース : PDB / ID : 3jvj 構造の表示 ダウンロードとリンクタイトル Crystal structure of the bromodomain 1 in mouse Brd4 要素Bromodomain-containing protein 4 詳細 キーワード SIGNALING PROTEIN / bromodomain / alpha helical / N-acetyl lysine binding domain / Nucleus / Phosphoprotein機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
GTP-dependent protein kinase activity / cyclin/CDK positive transcription elongation factor complex / inner cell mass cell proliferation / RNA polymerase II C-terminal domain binding / positive regulation of T-helper 17 cell lineage commitment / positive regulation of G2/M transition of mitotic cell cycle / RNA polymerase II CTD heptapeptide repeat kinase activity / condensed nuclear chromosome / chromosome segregation / positive regulation of transcription elongation by RNA polymerase II ... GTP-dependent protein kinase activity / cyclin/CDK positive transcription elongation factor complex / inner cell mass cell proliferation / RNA polymerase II C-terminal domain binding / positive regulation of T-helper 17 cell lineage commitment / positive regulation of G2/M transition of mitotic cell cycle / RNA polymerase II CTD heptapeptide repeat kinase activity / condensed nuclear chromosome / chromosome segregation / positive regulation of transcription elongation by RNA polymerase II / transcription coregulator activity / lysine-acetylated histone binding / p53 binding / regulation of inflammatory response / positive regulation of canonical NF-kappaB signal transduction / chromatin remodeling / chromatin binding / regulation of DNA-templated transcription / chromatin / regulation of transcription by RNA polymerase II / positive regulation of DNA-templated transcription / positive regulation of transcription by RNA polymerase II / DNA binding / nucleus 類似検索 - 分子機能 Bromodomain protein 4, C-terminal / C-terminal domain of bromodomain protein 4 / NET domain superfamily / : / NET domain profile. / Brdt, bromodomain, repeat II / Brdt, bromodomain, repeat I / NET domain / Bromodomain extra-terminal - transcription regulation / Bromodomain-like ... Bromodomain protein 4, C-terminal / C-terminal domain of bromodomain protein 4 / NET domain superfamily / : / NET domain profile. / Brdt, bromodomain, repeat II / Brdt, bromodomain, repeat I / NET domain / Bromodomain extra-terminal - transcription regulation / Bromodomain-like / Histone Acetyltransferase; Chain A / Bromodomain, conserved site / Bromodomain signature. / Bromodomain / Bromodomain profile. / bromo domain / Bromodomain / Bromodomain-like superfamily / Up-down Bundle / Mainly Alpha 類似検索 - ドメイン・相同性生物種 Mus musculus (ハツカネズミ)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 1.55 Å 詳細データ登録者 Vollmuth, F. / Blankenfeldt, W. / Geyer, M. 引用ジャーナル : J.Biol.Chem. / 年 : 2009タイトル : Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution著者 : Vollmuth, F. / Blankenfeldt, W. / Geyer, M. 履歴 登録 2009年9月17日 登録サイト : RCSB / 処理サイト : PDBJ改定 1.0 2009年10月13日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Non-polymer description / Version format compliance改定 1.2 2023年11月1日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ref_seq_dif / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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