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Structure paper

TitleStructures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution
Journal, issue, pagesJ. Biol. Chem., Vol. 284, Page 36547-36556, Year 2009
Publish dateSep 17, 2009 (structure data deposition date)
AuthorsVollmuth, F. / Blankenfeldt, W. / Geyer, M.
External linksJ. Biol. Chem. / PubMed:19828451
MethodsX-ray diffraction
Resolution1.2 - 1.8 Å
Structure data

PDB-3jvj:
Crystal structure of the bromodomain 1 in mouse Brd4
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-3jvk:
Crystal structure of bromodomain 1 of mouse Brd4 in complex with histone H3-K(ac)14
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-3jvl:
Crystal structure of bromodomain 2 of mouse Brd4
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

PDB-3jvm:
Crystal structure of bromodomain 2 of mouse Brd4
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-BME:
BETA-MERCAPTOETHANOL

Source
  • mus musculus (house mouse)
KeywordsSIGNALING PROTEIN / bromodomain / alpha helical / N-acetyl lysine binding domain / Nucleus / Phosphoprotein / N-acetyl lysine recognition

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