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- PDB-3iwu: Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourat... -
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Open data
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Basic information
Entry | Database: PDB / ID: 3iwu | ||||||
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Title | Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase | ||||||
![]() | 5-hydroxyisourate hydrolase | ||||||
![]() | HYDROLASE / HIUase / Transthyretin / TRP / thyroid hormones / molecular evolution / Peroxisome / Purine metabolism | ||||||
Function / homology | ![]() hydroxyisourate hydrolase / hydroxyisourate hydrolase activity / hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides / urate catabolic process / purine nucleobase metabolic process / peroxisome Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Cendron, L. / Ramazzina, I. / Berni, R. / Percudani, R. / Zanotti, G. | ||||||
![]() | ![]() Title: Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign. Authors: Cendron, L. / Ramazzina, I. / Percudani, R. / Rasore, C. / Zanotti, G. / Berni, R. #1: ![]() Title: Structure of zebra fish HIUase: insights into evolution of an enzyme to a hormone transporter Authors: Zanotti, G. / Cendron, L. / Ramazzina, I. / Folli, C. / Percudani, R. / Berni, R. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 204.8 KB | Display | ![]() |
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PDB format | ![]() | 164.2 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
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-Related structure data
Related structure data | ![]() 3iwvC ![]() 3q1eC ![]() 2h1xS S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Assembly
Deposited unit | ![]()
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1 / Refine code: 5
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