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Yorodumi- PDB-3iwu: Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourat... -
+Open data
-Basic information
Entry | Database: PDB / ID: 3iwu | ||||||
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Title | Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase | ||||||
Components | 5-hydroxyisourate hydrolase | ||||||
Keywords | HYDROLASE / HIUase / Transthyretin / TRP / thyroid hormones / molecular evolution / Peroxisome / Purine metabolism | ||||||
Function / homology | Function and homology information hydroxyisourate hydrolase / hydroxyisourate hydrolase activity / hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides / urate catabolic process / purine nucleobase metabolic process / peroxisome Similarity search - Function | ||||||
Biological species | Danio rerio (zebrafish) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.3 Å | ||||||
Authors | Cendron, L. / Ramazzina, I. / Berni, R. / Percudani, R. / Zanotti, G. | ||||||
Citation | Journal: J.Mol.Biol. / Year: 2011 Title: Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign. Authors: Cendron, L. / Ramazzina, I. / Percudani, R. / Rasore, C. / Zanotti, G. / Berni, R. #1: Journal: J.Mol.Biol. / Year: 2006 Title: Structure of zebra fish HIUase: insights into evolution of an enzyme to a hormone transporter Authors: Zanotti, G. / Cendron, L. / Ramazzina, I. / Folli, C. / Percudani, R. / Berni, R. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 3iwu.cif.gz | 204.8 KB | Display | PDBx/mmCIF format |
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PDB format | pdb3iwu.ent.gz | 164.2 KB | Display | PDB format |
PDBx/mmJSON format | 3iwu.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 3iwu_validation.pdf.gz | 485 KB | Display | wwPDB validaton report |
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Full document | 3iwu_full_validation.pdf.gz | 501.9 KB | Display | |
Data in XML | 3iwu_validation.xml.gz | 42.1 KB | Display | |
Data in CIF | 3iwu_validation.cif.gz | 59.6 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/iw/3iwu ftp://data.pdbj.org/pub/pdb/validation_reports/iw/3iwu | HTTPS FTP |
-Related structure data
Related structure data | 3iwvC 3q1eC 2h1xS S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data |
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-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1 / Refine code: 5
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