登録情報 | データベース: PDB / ID: 3ggf |
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タイトル | Crystal structure of human Serine/threonine-protein kinase MST4 in complex with an quinazolin |
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要素 | Serine/threonine-protein kinase MST4 |
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キーワード | TRANSFERASE / Serine/threonine-protein kinase / Structural Genomics / Structural Genomics Consortium / SGC / Apoptosis / ATP-binding / Golgi apparatus / Kinase / Magnesium / Metal-binding / Nucleotide-binding / Phosphoprotein |
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機能・相同性 | 機能・相同性情報
microvillus assembly / FAR/SIN/STRIPAK complex / vesicle membrane / Golgi-associated vesicle / Apoptotic cleavage of cellular proteins / cellular response to starvation / negative regulation of cell migration / cell periphery / cellular response to oxidative stress / regulation of apoptotic process ...microvillus assembly / FAR/SIN/STRIPAK complex / vesicle membrane / Golgi-associated vesicle / Apoptotic cleavage of cellular proteins / cellular response to starvation / negative regulation of cell migration / cell periphery / cellular response to oxidative stress / regulation of apoptotic process / protein autophosphorylation / non-specific serine/threonine protein kinase / protein kinase activity / intracellular signal transduction / apical plasma membrane / protein phosphorylation / protein serine kinase activity / protein serine/threonine kinase activity / apoptotic process / perinuclear region of cytoplasm / Golgi apparatus / magnesium ion binding / protein homodimerization activity / extracellular exosome / ATP binding / identical protein binding / membrane / cytosol / cytoplasm類似検索 - 分子機能 MST4, kinase domain / Programmed cell death protein 10, dimerisation domain superfamily / : / Programmed cell death protein 10, dimerisation domain / : / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Phosphorylase Kinase; domain 1 / Phosphorylase Kinase; domain 1 / Protein kinase domain ...MST4, kinase domain / Programmed cell death protein 10, dimerisation domain superfamily / : / Programmed cell death protein 10, dimerisation domain / : / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Phosphorylase Kinase; domain 1 / Phosphorylase Kinase; domain 1 / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / 2-Layer Sandwich / Orthogonal Bundle / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 : / Chem-GVD / Serine/threonine-protein kinase 26類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.35 Å |
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データ登録者 | Chaikuad, A. / Rellos, P. / Eidarus, S. / Das, S. / Pike, A.C.W. / Sethi, R. / Fedorov, O. / Savitsky, P. / Roos, A.K. / Filippakopoulos, P. ...Chaikuad, A. / Rellos, P. / Eidarus, S. / Das, S. / Pike, A.C.W. / Sethi, R. / Fedorov, O. / Savitsky, P. / Roos, A.K. / Filippakopoulos, P. / Arrowsmith, C.H. / Edwards, A.M. / Weigelt, J. / Bountra, C. / von Delft, F. / Knapp, S. / Structural Genomics Consortium (SGC) |
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引用 | ジャーナル: Plos One / 年: 2010 タイトル: Structural comparison of human mammalian ste20-like kinases 著者: Record, C.J. / Chaikuad, A. / Rellos, P. / Das, S. / Pike, A.C. / Fedorov, O. / Marsden, B.D. / Knapp, S. / Lee, W.H. |
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履歴 | 登録 | 2009年2月27日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2009年3月24日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 1.2 | 2018年1月31日 | Group: Structure summary / カテゴリ: audit_author / Item: _audit_author.name |
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改定 1.3 | 2023年9月6日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_conn_angle / struct_conn / struct_ncs_dom_lim / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_asym_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr2_auth_seq_id / _pdbx_struct_conn_angle.ptnr2_label_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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