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Open data
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Basic information
Entry | Database: PDB / ID: 3bic | ||||||
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Title | Crystal structure of human methylmalonyl-CoA mutase | ||||||
![]() | Methylmalonyl-CoA mutase, mitochondrial precursor | ||||||
![]() | ISOMERASE / organic aciduria / methylmalonyl CoA mutase deficiency / metabolic disease / Structural Genomics / Structural Genomics Consortium / SGC / Cobalamin / Cobalt / Disease mutation / Metal-binding / Mitochondrion / Transit peptide | ||||||
Function / homology | ![]() succinyl-CoA biosynthetic process / Defective MMAA causes MMA, cblA type / Defective MUT causes MMAM / Propionyl-CoA catabolism / propionate metabolic process, methylmalonyl pathway / methylmalonyl-CoA mutase / Cobalamin (Cbl) metabolism / methylmalonyl-CoA mutase activity / modified amino acid binding / homocysteine metabolic process ...succinyl-CoA biosynthetic process / Defective MMAA causes MMA, cblA type / Defective MUT causes MMAM / Propionyl-CoA catabolism / propionate metabolic process, methylmalonyl pathway / methylmalonyl-CoA mutase / Cobalamin (Cbl) metabolism / methylmalonyl-CoA mutase activity / modified amino acid binding / homocysteine metabolic process / cobalamin binding / post-embryonic development / positive regulation of GTPase activity / mitochondrial matrix / GTPase activity / protein homodimerization activity / mitochondrion / identical protein binding / metal ion binding / cytoplasm Similarity search - Function | ||||||
Biological species | ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Ugochukwu, E. / Kochan, G. / Pantic, N. / Parizotto, E. / Pilka, E.S. / Pike, A.C.W. / Gileadi, O. / von Delft, F. / Arrowsmith, C.H. / Weigelt, J. ...Ugochukwu, E. / Kochan, G. / Pantic, N. / Parizotto, E. / Pilka, E.S. / Pike, A.C.W. / Gileadi, O. / von Delft, F. / Arrowsmith, C.H. / Weigelt, J. / Edwards, A.M. / Oppermann, U. / Structural Genomics Consortium (SGC) | ||||||
![]() | ![]() Title: Structures of the human GTPase MMAA and vitamin B12-dependent methylmalonyl-CoA mutase and insight into their complex formation. Authors: Froese, D.S. / Kochan, G. / Muniz, J.R. / Wu, X. / Gileadi, C. / Ugochukwu, E. / Krysztofinska, E. / Gravel, R.A. / Oppermann, U. / Yue, W.W. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 274.5 KB | Display | ![]() |
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PDB format | ![]() | 217.5 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 444.2 KB | Display | ![]() |
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Full document | ![]() | 452.7 KB | Display | |
Data in XML | ![]() | 47.2 KB | Display | |
Data in CIF | ![]() | 65.3 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 2wwwC ![]() 2xijC ![]() 2xiqC ![]() 1reqS S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Assembly
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Noncrystallographic symmetry (NCS) | NCS domain:
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