登録情報 データベース : PDB / ID : 2z5c 構造の表示 ダウンロードとリンクタイトル Crystal Structure of a Novel Chaperone Complex for Yeast 20S Proteasome Assembly 要素Proteasome component PUP2 Protein YPL144W Uncharacterized protein YLR021W 詳細キーワード CHAPERONE/HYDROLASE / PROTEASOME / Chaperone / S. cerevisiae / CHAPERONE-HYDROLASE COMPLEX機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
nuclear-transcribed mRNA catabolic process, non-stop decay / Cross-presentation of soluble exogenous antigens (endosomes) / TNFR2 non-canonical NF-kB pathway / proteasomal ubiquitin-independent protein catabolic process / Ubiquitin Mediated Degradation of Phosphorylated Cdc25A / Regulation of PTEN stability and activity / KEAP1-NFE2L2 pathway / CDK-mediated phosphorylation and removal of Cdc6 / Neddylation / FBXL7 down-regulates AURKA during mitotic entry and in early mitosis ... nuclear-transcribed mRNA catabolic process, non-stop decay / Cross-presentation of soluble exogenous antigens (endosomes) / TNFR2 non-canonical NF-kB pathway / proteasomal ubiquitin-independent protein catabolic process / Ubiquitin Mediated Degradation of Phosphorylated Cdc25A / Regulation of PTEN stability and activity / KEAP1-NFE2L2 pathway / CDK-mediated phosphorylation and removal of Cdc6 / Neddylation / FBXL7 down-regulates AURKA during mitotic entry and in early mitosis / Orc1 removal from chromatin / MAPK6/MAPK4 signaling / proteasome storage granule / Antigen processing: Ubiquitination & Proteasome degradation / proteasome assembly / chaperone-mediated protein complex assembly / proteasome core complex, alpha-subunit complex / Ub-specific processing proteases / Neutrophil degranulation / proteasome complex / proteasome-mediated ubiquitin-dependent protein catabolic process / protein-containing complex / nucleus / cytoplasm 類似検索 - 分子機能 Ribosomal Protein S5; domain 2 - #100 / Proteasome chaperone 3/4 / 20S proteasome chaperone assembly proteins 3 and 4 / Ribosomal Protein S5; domain 2 - #90 / Aminohydrolase, N-terminal nucleophile (Ntn) domain / Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 / Ribosomal Protein S5; domain 2 / Proteasome subunit alpha5 / Proteasome subunit A N-terminal signature / Proteasome alpha-type subunits signature. ... Ribosomal Protein S5; domain 2 - #100 / Proteasome chaperone 3/4 / 20S proteasome chaperone assembly proteins 3 and 4 / Ribosomal Protein S5; domain 2 - #90 / Aminohydrolase, N-terminal nucleophile (Ntn) domain / Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 / Ribosomal Protein S5; domain 2 / Proteasome subunit alpha5 / Proteasome subunit A N-terminal signature / Proteasome alpha-type subunits signature. / Proteasome alpha-subunit, N-terminal domain / Proteasome subunit A N-terminal signature Add an annotation / : / Proteasome alpha-type subunit / Proteasome alpha-type subunit profile. / Proteasome subunit / Proteasome, subunit alpha/beta / Nucleophile aminohydrolases, N-terminal / 4-Layer Sandwich / 2-Layer Sandwich / Alpha Beta 類似検索 - ドメイン・相同性 Proteasome subunit alpha type-5 / Proteasome chaperone 3 / Proteasome chaperone 4 類似検索 - 構成要素生物種 Saccharomyces cerevisiae (パン酵母)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.9 Å 詳細データ登録者 Yashiroda, H. / Mizushima, T. / Okamoto, K. / Kameyama, T. / Hayashi, H. / Kishimoto, T. / Kasahara, M. / Kurimoto, E. / Sakata, E. / Suzuki, A. ...Yashiroda, H. / Mizushima, T. / Okamoto, K. / Kameyama, T. / Hayashi, H. / Kishimoto, T. / Kasahara, M. / Kurimoto, E. / Sakata, E. / Suzuki, A. / Hirano, Y. / Murata, S. / Kato, K. / Yamane, T. / Tanaka, K. 引用ジャーナル : Nat.Struct.Mol.Biol. / 年 : 2008タイトル : Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes著者: Yashiroda, H. / Mizushima, T. / Okamoto, K. / Kameyama, T. / Hayashi, H. / Kishimoto, T. / Niwa, S. / Kasahara, M. / Kurimoto, E. / Sakata, E. / Takagi, K. / Suzuki, A. / Hirano, Y. / Murata, ... 著者 : Yashiroda, H. / Mizushima, T. / Okamoto, K. / Kameyama, T. / Hayashi, H. / Kishimoto, T. / Niwa, S. / Kasahara, M. / Kurimoto, E. / Sakata, E. / Takagi, K. / Suzuki, A. / Hirano, Y. / Murata, S. / Kato, K. / Yamane, T. / Tanaka, K. 履歴 登録 2007年7月3日 登録サイト : PDBJ / 処理サイト : PDBJ改定 1.0 2008年1月22日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Version format compliance改定 1.2 2017年8月9日 Group : Data collection / Source and taxonomy / カテゴリ : diffrn_detector / entity_src_gen / Item : _diffrn_detector.detector改定 1.3 2023年11月1日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ncs_dom_lim / struct_ref_seq_dif Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ref_seq_dif.details
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