- PDB-1h30: C-terminal LG domain pair of human Gas6 -
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Basic information
Entry
Database: PDB / ID: 1h30
Title
C-terminal LG domain pair of human Gas6
Components
GROWTH-ARREST-SPECIFIC PROTEIN
Keywords
LAMININ G-DOMAIN PROTEIN / VITAMIN K-DEPENDENT PROTEIN / AXL/SKY/MER LIGAND / LAMININ G- LIKE DOMAIN / EGF-LIKE DOMAIN / CALCIUM-BINDING
Function / homology
Function and homology information
negative regulation of oligodendrocyte apoptotic process / negative regulation of renal albumin absorption / cellular response to vitamin K / positive regulation of glomerular filtration / positive regulation of natural killer cell differentiation / hematopoietic stem cell migration to bone marrow / B cell chemotaxis / cellular response to interferon-alpha / positive regulation of dendritic cell chemotaxis / myeloid cell apoptotic process ...negative regulation of oligodendrocyte apoptotic process / negative regulation of renal albumin absorption / cellular response to vitamin K / positive regulation of glomerular filtration / positive regulation of natural killer cell differentiation / hematopoietic stem cell migration to bone marrow / B cell chemotaxis / cellular response to interferon-alpha / positive regulation of dendritic cell chemotaxis / myeloid cell apoptotic process / extracellular matrix assembly / positive regulation of cytokine-mediated signaling pathway / negative regulation of interleukin-1 production / dendritic cell differentiation / negative regulation of biomineral tissue development / negative regulation of myeloid cell apoptotic process / negative regulation of dendritic cell apoptotic process / negative regulation of fibroblast apoptotic process / apoptotic cell clearance / fibroblast apoptotic process / enzyme-linked receptor protein signaling pathway / cell-substrate adhesion / phosphatidylserine binding / negative regulation of interleukin-6 production / cysteine-type endopeptidase inhibitor activity involved in apoptotic process / negative regulation of tumor necrosis factor production / negative regulation of type II interferon production / negative regulation of tumor necrosis factor-mediated signaling pathway / positive regulation of TOR signaling / positive regulation of protein kinase activity / animal organ regeneration / Gamma-carboxylation of protein precursors / Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus / negative regulation of endothelial cell apoptotic process / phagocytosis / Removal of aminoterminal propeptides from gamma-carboxylated proteins / positive regulation of phagocytosis / activation of protein kinase B activity / cellular response to starvation / viral genome replication / negative regulation of cysteine-type endopeptidase activity involved in apoptotic process / positive regulation of protein export from nucleus / platelet alpha granule lumen / protein localization to plasma membrane / Cell surface interactions at the vascular wall / cellular response to glucose stimulus / calcium ion transmembrane transport / Post-translational protein phosphorylation / neuron migration / receptor tyrosine kinase binding / cellular response to growth factor stimulus / Golgi lumen / Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) / positive regulation of fibroblast proliferation / blood coagulation / cellular response to xenobiotic stimulus / Platelet degranulation / protein-macromolecule adaptor activity / positive regulation of ERK1 and ERK2 cascade / positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / receptor-mediated virion attachment to host cell / cell surface receptor signaling pathway / receptor ligand activity / symbiont entry into host cell / positive regulation of protein phosphorylation / endoplasmic reticulum lumen / fusion of virus membrane with host plasma membrane / protein phosphorylation / signaling receptor binding / negative regulation of DNA-templated transcription / calcium ion binding / positive regulation of gene expression / negative regulation of apoptotic process / signal transduction / extracellular space / extracellular exosome / extracellular region / cytoplasm Similarity search - Function
#1: Journal: J.Biol.Chem. / Year: 1996 Title: Characterization of Gas6, a Member of the Superfamily of G Domain-Containing Proteins, as a Ligand for Rse and Axl Authors: Mark, M.R. / Chen, J. / Hammond, R.G. / Sadick, M. / Godowski, P.J.
History
Deposition
Aug 21, 2002
Deposition site: PDBE / Processing site: PDBE
Revision 1.0
Jan 30, 2003
Provider: repository / Type: Initial release
Revision 1.1
May 8, 2011
Group: Version format compliance
Revision 1.2
Jul 13, 2011
Group: Version format compliance
Remark 700
SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN ... SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN THE SHEET RECORDS BELOW, TWO SHEETS ARE DEFINED.
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