- PDB-2xnh: Structure and function of the Rad9-binding region of the DNA dama... -
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Basic information
Entry
Database: PDB / ID: 2xnh
Title
Structure and function of the Rad9-binding region of the DNA damage checkpoint adaptor TopBP1
Components
DNA TOPOISOMERASE 2-BINDING PROTEIN 1
Keywords
ISOMERASE / PHOSPHORYLATION / PROTEIN-PROTEIN INTERACTION / DNA REPAIR
Function / homology
Function and homology information
broken chromosome clustering / BRCA1-B complex / phosphorylation-dependent protein binding / chromatin-protein adaptor activity / homologous recombination / DNA replication checkpoint signaling / double-strand break repair via classical nonhomologous end joining / protein localization to site of double-strand break / mitotic DNA replication checkpoint signaling / HDR through Single Strand Annealing (SSA) ...broken chromosome clustering / BRCA1-B complex / phosphorylation-dependent protein binding / chromatin-protein adaptor activity / homologous recombination / DNA replication checkpoint signaling / double-strand break repair via classical nonhomologous end joining / protein localization to site of double-strand break / mitotic DNA replication checkpoint signaling / HDR through Single Strand Annealing (SSA) / DNA metabolic process / Impaired BRCA2 binding to RAD51 / response to ionizing radiation / double-strand break repair via alternative nonhomologous end joining / mitotic G2 DNA damage checkpoint signaling / site of DNA damage / Presynaptic phase of homologous DNA pairing and strand exchange / DNA replication initiation / chromosome organization / protein serine/threonine kinase activator activity / condensed nuclear chromosome / DNA damage checkpoint signaling / male germ cell nucleus / double-strand break repair via homologous recombination / G2/M DNA damage checkpoint / PML body / spindle pole / actin cytoskeleton / chromosome / site of double-strand break / Processing of DNA double-strand break ends / Regulation of TP53 Activity through Phosphorylation / nuclear body / DNA repair / centrosome / DNA damage response / DNA binding / nucleoplasm / identical protein binding / nucleus / plasma membrane / cytoplasm Similarity search - Function
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